Optimum Nutrition
THE BIOHACKING STANDARD
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Vitamin B2 (riboflavin) is an essential B vitamin with specific evidence for migraine prevention at 400mg/day (Boehnke 2004 Neurology RCT showing 59% reduction in migraine frequency; Schoenen 1998 established the dose). Dietary insufficiency of B2 is rare in Western diets. This SKU is 60 capsules of vitamin B2 with no per-capsule dose disclosed. For migraine prophylaxis the trial-evidenced dose is 400mg/day; RDA is 1.1-1.3mg/day — a 300x difference between deficiency-correction and migraine-therapy dose. Without per-capsule mg, buyers cannot dose intentionally for either use. Standard 55/100: legitimate isolated vitamin with real evidence for a specific therapeutic use, held down by no dose disclosure and no COA.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
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Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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