TruHealth™

Six-dimension breakdown

Why this scored 74/100

TruHealth is TruDiagnostic's epigenetic wellness-panel test — same Illumina Infinium MethylationEPIC BeadChip methodology as the flagship TruAge, processed at TruDiagnostic's CLIA-certified lab in Lexington, Kentucky, but reporting 105+ methylation-derived biomarkers across 19 biological systems (immune, metabolic, inflammatory, cardiovascular, neurocognitive, hepatic, renal, and more) rather than pure biological-age clocks. The underlying methodology is legitimate and well-published — DNA methylation at hundreds of thousands of CpG sites is a validated biomarker layer, and the systems-level panel builds on peer-reviewed epigenetic-clock literature (Horvath, Levine PhenoAge, Lu GrimAge, Belsky DunedinPACE). Analytical validity is strong (typical CV <3% for the underlying clocks); clinical utility is moderate because system-level methylation scores are population-validated but individual longitudinal interpretation over short windows is noisier than the marketing implies. Transparency is a genuine strength — TruDiagnostic co-authors much of the underlying peer-reviewed literature and publishes methodology openly. Value is the weakest dimension at $300-500 per test. Verified-tier epigenetic wellness test; not a substitute for clinical labs (LDL, HbA1c, TSH, etc.) that a primary-care physician orders for actual disease screening.

Evidence & sources

The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.

Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.

How to read the Evidence dimension

• 80–100: Multiple double-blind RCTs in indexed journals directly testing this product OR the exact ingredients at the exact dose.
• 60–79: Single double-blind RCT + supporting ingredient literature at the studied dose.
• 40–59: Open-label trials + ingredient literature; no product-specific double-blind evidence.
• 20–39: Ingredient literature only; no product-specific trials or trials in predatory venues.
• 0–19: No credible evidence base or unverifiable claims.

FAQ data has not been generated for this product yet. See the site FAQ for general questions.

Customer reviews

All the data we have on this product

Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.

VSF score

74 / 100

Tier

Verified

Category

Diagnostics testing

Subcategory

genetic dna

Last scored

August 29, 2026

Third-party certifications

None on record at time of scoring

Vendor

TruDiagnostic™

Product type

Epigenetic Test

Tags

Shopify Collective, TruDiagnosticTM

Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.