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TruDiagnostic's combined kit runs both flagship epigenetic panels — the TruAge biological-age clocks (OMICmAge, DunedinPACE, GrimAge-adjacent) and the TruHealth 19-system wellness biomarker panel — from a single saliva sample processed at TruDiagnostic's CLIA-certified Kentucky lab on Illumina Infinium MethylationEPIC BeadChip. 180+ epigenetic biomarkers reported in total. Combining both tests from one sample is meaningfully better value than purchasing them separately, which lifts the value dimension into the mid-70s (vs. 68 for TruHealth-alone). The underlying methodology is the best-published commercial biological-age testing on the market — Horvath 2013, Levine PhenoAge 2018, Lu GrimAge 2019, Belsky DunedinPACE 2022 — with TruDiagnostic scientists co-authoring several extensions. Analytical validity is strong (CV <3% for the core clocks). Clinical utility remains moderate rather than strong because individual short-term change interpretation is noisier than the marketing implies and no clock has FDA clearance as a disease-diagnostic device. Solid Verified-tier bundled diagnostic — the most defensible commercial offering in the direct-to-consumer epigenetic-age space, particularly for users planning longitudinal tracking of DunedinPACE.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
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Orthopedic Outfitters
TruDiagnostic™
Leaders Beauty & Wellness
DailySale
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