Orthopedic Outfitters
THE BIOHACKING STANDARD
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TruDiagnostic's TruAge is the leading commercial DNA-methylation biological-age test, processed at TruDiagnostic's own CLIA-certified lab in Kentucky. Reports biological age via peer-reviewed clocks including OMICmAge and DunedinPACE (Belsky et al., Nature Aging), and includes pace-of-aging estimates plus system-level (immune, metabolic, inflammatory) breakdowns. Methodology is well-documented — Infinium MethylationEPIC BeadChip run on saliva-derived DNA, with published reproducibility (CV typically <3% for the underlying clocks). Clinical utility for individual biohacking decisions is moderate: the clocks are validated at population level but longitudinal changes for a single individual are noisy over short windows. Data is retained; opt-in research use is disclosed. Value is the weakest dimension at $200-500 per test. Would move to Elite 85+ with lower price or bundled longitudinal tracking, and more explicit disclosure of clock noise floor for individual interpretation.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
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Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

Orthopedic Outfitters
TruDiagnostic™
TruDiagnostic™
Leaders Beauty & Wellness
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