Optimum Nutrition
THE BIOHACKING STANDARD
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Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
Tru Niagen 300mg — Niagen is ChromaDex's proprietary nicotinamide riboside (NR) with the most extensive human RCT literature of any NAD+ precursor (Martens 2018, Airhart 2017, Trammell 2016 on NAD+ elevation, PK, and safety). Regulatory advantage over NMN: NR has GRAS-affirmed status with FDA. Tru Niagen is the licensed consumer brand with real quality controls and transparent supply chain. 300mg is in the studied dose range. Held below Elite by (1) sold via 'Beauty Care Bag' reseller — buy direct from Tru Niagen for full brand-quality documentation; (2) sustainability profile thin; (3) higher per-serving cost than generic NAD-precursor products. Would move to Elite 85+ with direct-brand purchase channel + sustainability certification. Higher-scoring product in the NAD+ precursor category vs the NMN alternatives (see /blogs/news/nmn-gmp-certified-what-to-check-buyers-guide for the full NR-vs-NMN discussion).
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
Auto-generated from Vyvata's scoring data for this product. For general questions about the store (shipping, returns, wholesale), see the site FAQ.
Tru Niagen - Niagen 300 mg Nikotinamid Ribosid Supplement for Anti-Aging & Cellular Energy Support - 30 Capsules, categorized under Longevity & cellular health in the Supplements vertical. It is scored on the Vyvata Scoring Framework — an independent 6-dimension rubric applied uniformly to every product Vyvata lists.
78/100 overall — Verified tier (70–84 band). Per-dimension breakdown: Evidence 82, Formulation 80, Manufacturing 78, Safety 78, Transparency 75, Sustainability 55. Scored as of 2026-08-24.
Tru Niagen 300mg — Niagen is ChromaDex's proprietary nicotinamide riboside (NR) with the most extensive human RCT literature of any NAD+ precursor (Martens 2018, Airhart 2017, Trammell 2016 on NAD+ elevation, PK, and safety). Regulatory advantage over NMN: NR has GRAS-affirmed status with FDA. Tru Niagen is the licensed consumer brand with real quality controls and transparent supply chain. 300mg is in the studied dose range. Held below Elite by (1) sold via 'Beauty Care Bag' reseller — buy direct from Tru Niagen for full brand-quality documentation; (2) sustainability profile thin; (3) higher per-serving cost than generic NAD-precursor products. Would move to Elite 85+ with direct-brand purchase channel + sustainability certification. Higher-scoring product in the NAD+ precursor category vs the NMN alternatives (see /blogs/news/nmn-gmp-certified-what-to-check-buyers-guide for the full NR-vs-NMN discussion).
Strongest: Evidence at 82/100 (quality of published RCT support for the active ingredients at the label dose) and Formulation at 80/100 (dose adequacy, bioavailability form, and ingredient redundancy). Weakest: Transparency at 75/100 (dose disclosure vs proprietary blends, and honesty of marketing claims) and Sustainability at 55/100 (sourcing practices, packaging, and corporate practice). All six dimensions feed the overall Vyvata score; a weakness on any one dimension pulls the overall down proportionally.
No third-party certifications (NSF, USP, ConsumerLab, or equivalent) were on record at the time of scoring. This affects the Manufacturing dimension score. The manufacturer may test internally or have obtained certification more recently — check the current product label for the most up-to-date information.
Would move to Elite 85+ with direct-brand purchase channel + sustainability certification.
This is currently the highest-scoring product in the Longevity & cellular health subcategory of the Vyvata catalog. See the full ranked list of 131 scored longevity & cellular health products at https://vyvata.com/pages/best-longevity-and-cellular-health-supplements-ranked.
The Vyvata Scoring Framework rates every listed product 0–100 across six dimensions: Evidence, Formulation, Manufacturing, Safety, Transparency, and Sustainability. Tier bands: Elite 85–100 (top-tier evidence + formulation + manufacturing), Verified 70–84 (strong on most dimensions), Standard 50–69 (solid but with weaknesses called out), Rejected 0–49 (specific failures documented). Rejected products remain listed with reasons. Full methodology at https://vyvata.com/pages/methodology.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. For customer reviews and community discussion, search external platforms directly: Amazon (https://www.amazon.com/s?k=Tru%20Niagen%20-%20Niagen%20300%20mg%20Nikotinamid%20Ribosid%20Supplement%20for%20Anti-Aging%20%26%20Cellular%20Energy%20Support%20-%2030%20Capsules),Google(https://www.google.com/search?q=Tru%20Niagen%20-%20Niagen%20300%20mg%20Nikotinamid%20Ribosid%20Supplement%20for%20Anti-Aging%20%26%20Cellular%20Energy%20Support%20-%2030%20Capsules+reviews),Reddit(https://www.reddit.com/search/?q=Tru%20Niagen%20-%20Niagen%20300%20mg%20Nikotinamid%20Ribosid%20Supplement%20for%20Anti-Aging%20%26%20Cellular%20Energy%20Support%20-%2030%20Capsules%20review),andTrustpilot(https://www.trustpilot.com/search?query=Tru%20Niagen%20-%20Niagen%20300%20mg%20Nikotinamid%20Ribosid%20Supplement%20for%20Anti-Aging%20%26%20Cellular%20Energy%20Support%20-%2030%20Capsules).Vyvatadoesnotaggregate,republish,orlicensethosethird-partyreviews.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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