Optimum Nutrition
THE BIOHACKING STANDARD
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Super Aloe 250 is Ortho Molecular's lower-dose Cape aloe stimulant laxative — 250mg per capsule versus the 450mg strength product in this same batch. Same underlying mechanism (anthraquinone glycosides metabolized by gut bacteria into peristalsis-stimulating anthrones), same short-course intended use, same chronic-use safety concerns (dependence risk, historical carcinogenicity signal for chronic high-dose aloin). The lower dose is appropriate for milder cases and for users who found the 450mg strength produced too rapid or too dramatic a response. From a formulation perspective, having two dose strengths in the product line reflects thoughtful practitioner-brand titration options — a real quality signal. All the caveats from the Super Aloe 450 entry apply here, with slightly better safety margin at the lower dose because chronic-use exposure is proportionally lower. Standard tier consistent with the higher-dose sibling product, with safety dimension marginally better due to lower daily anthraquinone exposure.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
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