Solgar Methylcobalamin (Vitamin B12) 1000mcg 30 Nuggets

Six-dimension breakdown

Why this scored 68/100

Solgar Methylcobalamin 1000 mcg is a well-executed single-ingredient B12 supplement in the active methylcobalamin form (as opposed to cyanocobalamin, the synthetic form that requires enzymatic conversion). The 1000 mcg dose per nugget is well above the RDA (2.4 mcg/day) but appropriate for the supplement form — B12 absorption via intrinsic factor is saturable at low doses, so high oral doses rely on passive diffusion (~1-2% absorption of the total dose), and 1000 mcg reliably corrects most non-pernicious-anemia deficiency states. Sublingual nugget formulation adds modest additional absorption via oral mucosa, though the head-to-head evidence versus swallowed tablets at similar doses is mixed. Methylcobalamin is particularly reasonable for people with MTHFR variants or age-related reduced methylation capacity, though the 'active form' framing is often overstated in marketing. Solgar's manufacturing standards are strong (GMP-certified, kosher-parve certification, decades-established brand). Transparency capped by lack of routinely published per-lot third-party COAs. Solid Standard-tier B12 supplement — genuinely useful for the populations who need B12 supplementation (older adults, vegans/vegetarians, metformin or PPI users, malabsorption states, pernicious anemia when injectable is not required).

Evidence & sources

The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.

Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.

How to read the Evidence dimension

• 80–100: Multiple double-blind RCTs in indexed journals directly testing this product OR the exact ingredients at the exact dose.
• 60–79: Single double-blind RCT + supporting ingredient literature at the studied dose.
• 40–59: Open-label trials + ingredient literature; no product-specific double-blind evidence.
• 20–39: Ingredient literature only; no product-specific trials or trials in predatory venues.
• 0–19: No credible evidence base or unverifiable claims.

FAQ data has not been generated for this product yet. See the site FAQ for general questions.

Customer reviews

All the data we have on this product

Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.

VSF score

68 / 100

Tier

Standard

Category

Supplements

Subcategory

vitamins micronutrients

Last scored

August 29, 2026

Third-party certifications

None on record at time of scoring

Vendor

Pasteur Pharmacy

Product type

Vitamins & Supplements

Tags

Pasteur Pharmacy, Shopify Collective

Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.