Solgar L-Lysine 1000 mg 100 Tablets

Six-dimension breakdown

Why this scored 65/100

Solgar is a well-established US supplement brand with a public quality-control program (Gold Standard testing, published COAs on some SKUs) and a long track record in single-ingredient supplements. L-Lysine 1000 mg is a single-ingredient tablet at a disclosed dose — the exact profile Vyvata prefers for evaluability. Lysine has moderate evidence for reducing HSV-1 outbreak frequency and severity at doses of 1000-3000 mg/day (Griffith 1978, DiGiovanna 1984); the mechanism is competition with arginine for viral replication substrate. Also used in collagen synthesis, calcium absorption support, and general amino-acid replenishment. 1000 mg is at the low end of studied dose range for HSV — users chasing that outcome typically take 2-3 tablets/day, with some clinicians recommending higher acute doses during outbreak prodrome. Safety profile is favorable at these doses; caution with renal disease. Solid Standard entry — held from Verified by no visible USP or NSF verification on this SKU (Solgar does not universally carry those certifications despite in-house testing).

Evidence & sources

The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.

Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.

How to read the Evidence dimension

• 80–100: Multiple double-blind RCTs in indexed journals directly testing this product OR the exact ingredients at the exact dose.
• 60–79: Single double-blind RCT + supporting ingredient literature at the studied dose.
• 40–59: Open-label trials + ingredient literature; no product-specific double-blind evidence.
• 20–39: Ingredient literature only; no product-specific trials or trials in predatory venues.
• 0–19: No credible evidence base or unverifiable claims.

FAQ data has not been generated for this product yet. See the site FAQ for general questions.

Customer reviews

All the data we have on this product

Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.

VSF score

65 / 100

Tier

Standard

Category

Supplements

Subcategory

immune antioxidants

Last scored

August 30, 2026

Third-party certifications

None on record at time of scoring

Vendor

Pasteur Pharmacy

Product type

Vitamin Supplement

Tags

Pasteur Pharmacy, Shopify Collective

Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.