Optimum Nutrition
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[Rescored via evidence crawl] Previous score 72 → new 80. Evidence found: Gandia P, et al. A bioavailability study comparing two oral formulations containing zinc (Zn bis-glycinate vs Zn gluconate). Int J Vitam Nutr Res. 2007;77(4):243-8 (bisglycinate showed 43% higher AUC). | Albion Minerals patents and PK dossiers documenting zinc bisglycinate chelate absorption vs sulfate/oxide forms. | Wessels I, et al. Zinc supplementation ameliorates lymphocyte and other zinc-dependent processes. Adv Nutr. 2020 (baseline zinc RCT context).. Rationale: Solgar Chelated Zinc uses Albion zinc bisglycinate. Gandia 2007 head-to-head PK showed bisglycinate produced ~43% higher zinc AUC than gluconate at the same elemental zinc dose. TIER-B for the specific chelate form. 22 mg is a reasonable maintenance dose (RDA 8-11 mg; safe UL 40 mg). +8 uplift for well-documented formulation edge.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
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Solgar Chelated Zinc 22 Mg, 100 Tablets is a product from Solgar, categorized under Vitamins & foundational micronutrients in the Supplements vertical. It is scored on the Vyvata Scoring Framework — an independent 6-dimension rubric applied uniformly to every product Vyvata lists.
72/100 overall — Verified tier (70–84 band). Per-dimension breakdown: Evidence 78, Formulation 76, Manufacturing 74, Safety 72, Transparency 72, Sustainability 60. Scored as of 2026-08-24.
Solgar is a long-established practitioner-grade brand, and chelated zinc (typically zinc bisglycinate/gluconate) has meaningfully better bioavailability than zinc oxide — Gandia 2007 demonstrated superior absorption of amino-acid chelates versus oxide/sulfate. 22 mg falls within the studied 15-30 mg/day range for immune support (Hemila 2017 for cold duration) and is below the 40 mg UL, so safety is solid. Below Elite because Solgar rarely publishes SKU-level third-party testing and the specific chelate form isn't always named in the product title. Would move to Verified-high 78+ with the exact chelate identified (e.g., 'zinc bisglycinate') and a published CoA.
Strongest: Evidence at 78/100 (quality of published RCT support for the active ingredients at the label dose) and Formulation at 76/100 (dose adequacy, bioavailability form, and ingredient redundancy). Weakest: Transparency at 72/100 (dose disclosure vs proprietary blends, and honesty of marketing claims) and Sustainability at 60/100 (sourcing practices, packaging, and corporate practice). All six dimensions feed the overall Vyvata score; a weakness on any one dimension pulls the overall down proportionally.
No third-party certifications (NSF, USP, ConsumerLab, or equivalent) were on record at the time of scoring. This affects the Manufacturing dimension score. The manufacturer may test internally or have obtained certification more recently — check the current product label for the most up-to-date information.
Would move to Verified-high 78+ with the exact chelate identified (e.
The top-ranked vitamins & foundational micronutrients product in the Vyvata catalog is currently Thorne Basic Nutrients 2/Day at 89/100. See the full ranked list of 635 scored products in this subcategory at https://vyvata.com/pages/best-vitamins-and-foundational-micronutrients-supplements-ranked.
The Vyvata Scoring Framework rates every listed product 0–100 across six dimensions: Evidence, Formulation, Manufacturing, Safety, Transparency, and Sustainability. Tier bands: Elite 85–100 (top-tier evidence + formulation + manufacturing), Verified 70–84 (strong on most dimensions), Standard 50–69 (solid but with weaknesses called out), Rejected 0–49 (specific failures documented). Rejected products remain listed with reasons. Full methodology at https://vyvata.com/pages/methodology.
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The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
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Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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