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Reduced L-Glutathione Double Strength - FeaturingSetria
Reduced L-Glutathione Double Strength - FeaturingSetria
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Regular price
$22.19 USD
Regular price
Sale price
$22.19 USD
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The full picture
Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
72/100
Verified
Six-dimension breakdown
Evidence
72
Formulation
75
Manufacturing
74
Safety
72
Transparency
72
Sustainability
58
Why this scored 72/100
Double-strength reduced L-glutathione as Setria — the specific fermentation-derived branded ingredient studied by Richie 2015, which is the strongest oral GSH replication trial available (500-1000 mg/day for 6 months raised RBC and whole-body glutathione stores). Double-strength puts a single serving at or near the studied dose range, which most Setria SKUs don't achieve. Held to low Verified rather than Elite because oral GSH still faces first-pass hydrolysis versus liposomal or IV delivery. Would move up with per-lot COA disclosure.
Last scored: Full rubric →
Evidence & sources
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
How to read the Evidence dimension
- 80–100: Multiple double-blind RCTs in indexed journals directly testing this product OR the exact ingredients at the exact dose.
- 60–79: Single double-blind RCT + supporting ingredient literature at the studied dose.
- 40–59: Open-label trials + ingredient literature; no product-specific double-blind evidence.
- 20–39: Ingredient literature only; no product-specific trials or trials in predatory venues.
- 0–19: No credible evidence base or unverifiable claims.
Frequently asked questions
Auto-generated from Vyvata's scoring data for this product. For general questions about the store (shipping, returns, wholesale), see the site FAQ.
What is Reduced L-Glutathione Double Strength - FeaturingSetria?
Reduced L-Glutathione Double Strength - FeaturingSetria, categorized under Immune health & antioxidants in the Supplements vertical. It is scored on the Vyvata Scoring Framework — an independent 6-dimension rubric applied uniformly to every product Vyvata lists.
How does Reduced L-Glutathione Double Strength - FeaturingSetria score on the Vyvata rubric?
72/100 overall — Verified tier (70–84 band). Per-dimension breakdown: Formulation 75, Manufacturing 74, Evidence 72, Safety 72, Transparency 72, Sustainability 58. Scored as of 2026-08-24.
Why did Reduced L-Glutathione Double Strength - FeaturingSetria score in the Verified tier?
Double-strength reduced L-glutathione as Setria — the specific fermentation-derived branded ingredient studied by Richie 2015, which is the strongest oral GSH replication trial available (500-1000 mg/day for 6 months raised RBC and whole-body glutathione stores). Double-strength puts a single serving at or near the studied dose range, which most Setria SKUs don't achieve. Held to low Verified rather than Elite because oral GSH still faces first-pass hydrolysis versus liposomal or IV delivery. Would move up with per-lot COA disclosure.
What are the strongest and weakest aspects of this product?
Strongest: Formulation at 75/100 (dose adequacy, bioavailability form, and ingredient redundancy) and Manufacturing at 74/100 (third-party testing, GMP compliance, and facility audit status). Weakest: Transparency at 72/100 (dose disclosure vs proprietary blends, and honesty of marketing claims) and Sustainability at 58/100 (sourcing practices, packaging, and corporate practice). All six dimensions feed the overall Vyvata score; a weakness on any one dimension pulls the overall down proportionally.
Is Reduced L-Glutathione Double Strength - FeaturingSetria third-party tested?
No third-party certifications (NSF, USP, ConsumerLab, or equivalent) were on record at the time of scoring. This affects the Manufacturing dimension score. The manufacturer may test internally or have obtained certification more recently — check the current product label for the most up-to-date information.
Are there higher-scoring alternatives to Reduced L-Glutathione Double Strength - FeaturingSetria?
The top-ranked immune health & antioxidants product in the Vyvata catalog is currently PreserVision AREDS 2 Eye Vitamins, 210 Soft gels at 77/100. See the full ranked list of 590 scored products in this subcategory at https://vyvata.com/pages/best-immune-health-and-antioxidants-supplements-ranked.
What does the Vyvata score mean?
The Vyvata Scoring Framework rates every listed product 0–100 across six dimensions: Evidence, Formulation, Manufacturing, Safety, Transparency, and Sustainability. Tier bands: Elite 85–100 (top-tier evidence + formulation + manufacturing), Verified 70–84 (strong on most dimensions), Standard 50–69 (solid but with weaknesses called out), Rejected 0–49 (specific failures documented). Rejected products remain listed with reasons. Full methodology at https://vyvata.com/pages/methodology.
Where can I read customer reviews for Reduced L-Glutathione Double Strength - FeaturingSetria?
The Vyvata score measures product integrity against a published rubric, not customer sentiment. For customer reviews and community discussion, search external platforms directly: Amazon (https://www.amazon.com/s?k=Reduced%20L-Glutathione%20Double%20Strength%20-%20FeaturingSetria),Google(https://www.google.com/search?q=Reduced%20L-Glutathione%20Double%20Strength%20-%20FeaturingSetria+reviews),Reddit(https://www.reddit.com/search/?q=Reduced%20L-Glutathione%20Double%20Strength%20-%20FeaturingSetria%20review),andTrustpilot(https://www.trustpilot.com/search?query=Reduced%20L-Glutathione%20Double%20Strength%20-%20FeaturingSetria).Vyvatadoesnotaggregate,republish,orlicensethosethird-partyreviews.
Customer reviews
Reviews on other platforms
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
All the data we have on this product
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
- VSF score
- 72 / 100
- Tier
- Verified
- Category
- Supplements
- Subcategory
- immune antioxidants
- Last scored
- Third-party certifications
- None on record at time of scoring
- Vendor
- Swanson Vitamins
- Tags
- Shopify Collective, Swanson Vitamins
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.
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