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Pure Encapsulations Vitamin D3 Liquid - 22.5 ml | Health Supplement

Pure Encapsulations Vitamin D3 Liquid - 22.5 ml | Health Supplement

Brand ownership disclosure
Nestlé Health Science
Nestlé S.A. (SIX: NESN)
Acquired 2018 via $2.3B Atrium Innovations deal
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Regular price $29.57 USD
Regular price $34.79 USD Sale price $29.57 USD
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The full picture

Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →

82/100
Elite

Six-dimension breakdown

Evidence
78
Formulation
80
Manufacturing
80
Safety
74
Transparency
74
Sustainability
62

Why this scored 82/100

[Rescored via evidence crawl] Previous score 76 → new 82. Evidence found: Holick MF. Vitamin D deficiency. N Engl J Med. 2007;357(3):266-281. | Pure Encapsulations Vitamin D3 Liquid: cholecalciferol in MCT oil base for flexible dosing.. Rationale: Liquid D3 in MCT enables precise, flexible dosing (drop-based titration) — ideal for pediatric, elderly, or anyone requiring non-standard doses guided by 25(OH)D testing. Practitioner-grade. Elite tier.

Last scored: Full rubric →

Evidence & sources

The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.

Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.

How to read the Evidence dimension

  • 80–100: Multiple double-blind RCTs in indexed journals directly testing this product OR the exact ingredients at the exact dose.
  • 60–79: Single double-blind RCT + supporting ingredient literature at the studied dose.
  • 40–59: Open-label trials + ingredient literature; no product-specific double-blind evidence.
  • 20–39: Ingredient literature only; no product-specific trials or trials in predatory venues.
  • 0–19: No credible evidence base or unverifiable claims.

Frequently asked questions

Auto-generated from Vyvata's scoring data for this product. For general questions about the store (shipping, returns, wholesale), see the site FAQ.

What is Pure Encapsulations Vitamin D3 Liquid - 22.5 ml | Health Supplement?

Pure Encapsulations Vitamin D3 Liquid - 22.5 ml | Health Supplement is a product from Pure Encapsulations, categorized under Vitamins & foundational micronutrients in the Supplements vertical. It is scored on the Vyvata Scoring Framework — an independent 6-dimension rubric applied uniformly to every product Vyvata lists.

How does Pure Encapsulations Vitamin D3 Liquid - 22.5 ml | Health Supplement score on the Vyvata rubric?

76/100 overall — Verified tier (70–84 band). Per-dimension breakdown: Formulation 80, Manufacturing 80, Evidence 78, Safety 74, Transparency 74, Sustainability 62. Scored as of 2026-08-24.

Why did Pure Encapsulations Vitamin D3 Liquid - 22.5 ml | Health Supplement score in the Verified tier?

Pure Encapsulations is a top-tier practitioner brand (Atrium Innovations/Nestle Health Science) with hypoallergenic sourcing, no unnecessary excipients, and independent testing on every lot. Liquid D3 in an MCT-oil carrier is arguably the ideal delivery vehicle for a fat-soluble vitamin — better absorption than dry tablets (Grossmann 2010) and precise dose titration via dropper. D3 evidence is extensive (Martineau 2017 immune, Bischoff-Ferrari 2009 bone). The reseller-layer distribution (Beauty Care Bag) doesn't affect the underlying product quality. Below Elite because sustainability chain for lanolin-derived D3 isn't documented at SKU level. Would move to Elite 85+ with sustainability sourcing detail and NSF certification.

What are the strongest and weakest aspects of this product?

Strongest: Formulation at 80/100 (dose adequacy, bioavailability form, and ingredient redundancy) and Manufacturing at 80/100 (third-party testing, GMP compliance, and facility audit status). Weakest: Transparency at 74/100 (dose disclosure vs proprietary blends, and honesty of marketing claims) and Sustainability at 62/100 (sourcing practices, packaging, and corporate practice). All six dimensions feed the overall Vyvata score; a weakness on any one dimension pulls the overall down proportionally.

Is Pure Encapsulations Vitamin D3 Liquid - 22.5 ml | Health Supplement third-party tested?

No third-party certifications (NSF, USP, ConsumerLab, or equivalent) were on record at the time of scoring. This affects the Manufacturing dimension score. The manufacturer may test internally or have obtained certification more recently — check the current product label for the most up-to-date information.

What would move Pure Encapsulations Vitamin D3 Liquid - 22.5 ml | Health Supplement to a higher tier?

Would move to Elite 85+ with sustainability sourcing detail and NSF certification.

Are there higher-scoring alternatives to Pure Encapsulations Vitamin D3 Liquid - 22.5 ml | Health Supplement?

The top-ranked vitamins & foundational micronutrients product in the Vyvata catalog is currently Thorne Basic Nutrients 2/Day at 89/100. See the full ranked list of 635 scored products in this subcategory at https://vyvata.com/pages/best-vitamins-and-foundational-micronutrients-supplements-ranked.

What does the Vyvata score mean?

The Vyvata Scoring Framework rates every listed product 0–100 across six dimensions: Evidence, Formulation, Manufacturing, Safety, Transparency, and Sustainability. Tier bands: Elite 85–100 (top-tier evidence + formulation + manufacturing), Verified 70–84 (strong on most dimensions), Standard 50–69 (solid but with weaknesses called out), Rejected 0–49 (specific failures documented). Rejected products remain listed with reasons. Full methodology at https://vyvata.com/pages/methodology.

Where can I read customer reviews for Pure Encapsulations Vitamin D3 Liquid - 22.5 ml | Health Supplement?

Customer reviews

Reviews on other platforms

The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.

All the data we have on this product

Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.

VSF score
82 / 100
Tier
Elite
Category
Supplements
Subcategory
vitamins micronutrients
Last scored
Third-party certifications
None on record at time of scoring
Vendor
Beauty Care Bag
Product type
Vitamin & Supplement
Tags
Beauty Care Bag, Shopify Collective

Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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