Optimum Nutrition
THE BIOHACKING STANDARD
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A 'potassium concentrate' whose product description erroneously describes calcium — a copy-paste labelling error where the description text discusses calcium's role in bones and muscles rather than potassium. That labelling error alone would justify a Rejected tier under misleading_naming/misleading_labelling. Setting that aside, potassium is an essential mineral (adequate intake 3400 mg/day for men, 2600 for women) and most Americans consume below AI. Real deficiency is documented and can be corrected. However, supplemental potassium in dose forms above 99 mg per pill is FDA-restricted for a specific safety reason: high-dose potassium can cause life-threatening hyperkalaemia in users with kidney disease, on ACE inhibitors/ARBs, or on potassium-sparing diuretics, and undisclosed-dose liquid potassium supplements bypass that safety architecture. Rejected on both labelling error and safety-window narrowness.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
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Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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