Optimum Nutrition
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Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
Ortho Molecular Products' Mag Threonate uses licensed Magtein-format magnesium L-threonate — the only magnesium form shown in animal models to elevate brain magnesium concentration meaningfully (Slutsky 2010 Neuron — the anchor paper showing cognitive-memory improvement in aged rats via CSF Mg elevation), with follow-up human data on cognitive function in older adults (Liu 2016 J Alzheimers Dis). OMP is a legitimate practitioner-only brand with NSF-registered facility and per-lot COA availability. Formulation matches the studied 1500–2000 mg/day Magtein dose across capsules. Held below Elite because human RCT evidence remains limited (small trials, industry-linked), and this dose is stimulating for some people (evening use can disrupt sleep). Would move to Elite with additional independently-funded human trials at this dose.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
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Ortho Molecular Products Mag Threonate 60 Capsules, categorized under Cognitive health & nootropics in the Supplements vertical. It is scored on the Vyvata Scoring Framework — an independent 6-dimension rubric applied uniformly to every product Vyvata lists.
75/100 overall — Verified tier (70–84 band). Per-dimension breakdown: Formulation 82, Manufacturing 78, Transparency 76, Evidence 72, Safety 72, Sustainability 55. Scored as of 2026-08-24.
Ortho Molecular Products' Mag Threonate uses licensed Magtein-format magnesium L-threonate — the only magnesium form shown in animal models to elevate brain magnesium concentration meaningfully (Slutsky 2010 Neuron — the anchor paper showing cognitive-memory improvement in aged rats via CSF Mg elevation), with follow-up human data on cognitive function in older adults (Liu 2016 J Alzheimers Dis). OMP is a legitimate practitioner-only brand with NSF-registered facility and per-lot COA availability. Formulation matches the studied 1500–2000 mg/day Magtein dose across capsules. Held below Elite because human RCT evidence remains limited (small trials, industry-linked), and this dose is stimulating for some people (evening use can disrupt sleep). Would move to Elite with additional independently-funded human trials at this dose.
Strongest: Formulation at 82/100 (dose adequacy, bioavailability form, and ingredient redundancy) and Manufacturing at 78/100 (third-party testing, GMP compliance, and facility audit status). Weakest: Safety at 72/100 (adverse-event profile, interaction risk, and dose ceiling) and Sustainability at 55/100 (sourcing practices, packaging, and corporate practice). All six dimensions feed the overall Vyvata score; a weakness on any one dimension pulls the overall down proportionally.
No third-party certifications (NSF, USP, ConsumerLab, or equivalent) were on record at the time of scoring. This affects the Manufacturing dimension score. The manufacturer may test internally or have obtained certification more recently — check the current product label for the most up-to-date information.
Would move to Elite with additional independently-funded human trials at this dose.
The top-ranked cognitive health & nootropics product in the Vyvata catalog is currently Nordic Naturals Ultimate Omega 2X – High-Potency Fish Oil | 2150 mg EPA & DHA | Lemon Flavor, 120 Softgels at 87/100. See the full ranked list of 212 scored products in this subcategory at https://vyvata.com/pages/best-cognitive-health-and-nootropics-supplements-ranked.
The Vyvata Scoring Framework rates every listed product 0–100 across six dimensions: Evidence, Formulation, Manufacturing, Safety, Transparency, and Sustainability. Tier bands: Elite 85–100 (top-tier evidence + formulation + manufacturing), Verified 70–84 (strong on most dimensions), Standard 50–69 (solid but with weaknesses called out), Rejected 0–49 (specific failures documented). Rejected products remain listed with reasons. Full methodology at https://vyvata.com/pages/methodology.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. For customer reviews and community discussion, search external platforms directly: Amazon (https://www.amazon.com/s?k=Ortho%20Molecular%20Products%20Mag%20Threonate%2060%20Capsules),Google(https://www.google.com/search?q=Ortho%20Molecular%20Products%20Mag%20Threonate%2060%20Capsules+reviews),Reddit(https://www.reddit.com/search/?q=Ortho%20Molecular%20Products%20Mag%20Threonate%2060%20Capsules%20review),andTrustpilot(https://www.trustpilot.com/search?query=Ortho%20Molecular%20Products%20Mag%20Threonate%2060%20Capsules).Vyvatadoesnotaggregate,republish,orlicensethosethird-partyreviews.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
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Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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