Optimum Nutrition
THE BIOHACKING STANDARD
Welcome to our store
Couldn't load pickup availability
Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
Turkey tail (Trametes versicolor, Coriolus versicolor) has one of the more robust research portfolios in the medicinal mushroom space, driven by two isolated polysaccharopeptide fractions — PSK (Krestin) and PSP — that have been approved and widely used as adjuvant cancer therapy in Japan since the 1980s. PSK is the second-most-widely used oncology adjuvant in Japan for gastric, colorectal, and lung cancer supportive care, with meta-analyses showing modest survival benefit when added to chemotherapy. This is the strongest published cancer-adjuvant evidence for any medicinal mushroom fraction. The oral consumer tincture does not deliver isolated PSK/PSP at Japanese-clinical doses, but a fruit-body triple-extract does capture the beta-glucan and polysaccharopeptide fractions that underlie the pharmacology. Turkey tail is also one of the safer mushrooms — no meaningful drug interactions, minimal contraindications, well tolerated in long-term use. Mycoterra's fruit-body sourcing is again the appropriate quality signal. Standard tier reflecting the strongest evidence-base within the Mycoterra lineup for an immune-support mushroom, tempered by the tincture form not being the exact PSK/PSP isolate form studied in oncology trials.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

Optimum Nutrition
Onnit
WOW MD LLC
Prevagen
Find Your Protocol
A few quick questions about your goals and current concerns. We'll build a tailored protocol — a Basics list of essentials plus a comprehensive Biohackers list — across all Vyvata categories.
No signup required · Your protocol is private to you