Optimum Nutrition
THE BIOHACKING STANDARD
Welcome to our store
Couldn't load pickup availability
Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
Nutricost is a mid-market single-ingredient supplement brand (Utah-based, Vitasource-affiliated) with reasonable manufacturing (cGMP-registered facility, generally accurate labels). This product is 500mg Coleus forskohlii extract per serving, but the label does not disclose the forskolin standardization percentage — most clinically-studied Coleus products use 10% forskolin (Godard 2005 fat-loss study used 250mg twice daily of 10% standardized ForsLean). Without a standardization percentage disclosed, buyers cannot confirm they are getting the studied dose. Beyond the standardization gap, the evidence for Coleus forskohlii in weight loss is weak: Godard 2005 showed body composition changes in overweight men (n=30) but Henderson 2005 in overweight women (n=23) found no fat loss. Meta-analytic evidence is absent. Coleus can lower blood pressure, has anti-platelet activity, and interacts with anticoagulants — safety flag. The evidence gap plus the standardization gap keep this in Rejected, not on auto-fail but on cumulative dimension weakness.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

Optimum Nutrition
Onnit
WOW MD LLC
Prevagen
Find Your Protocol
A few quick questions about your goals and current concerns. We'll build a tailored protocol — a Basics list of essentials plus a comprehensive Biohackers list — across all Vyvata categories.
No signup required · Your protocol is private to you