Optimum Nutrition
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Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
Nutrex LIPO-6 NightTime is a 'sleep + weight loss' combo product — a category with essentially zero RCT support for the compound claim. Typically stacks melatonin, valerian, GABA, plus fat-burner actives. Combining sleep aids with metabolic actives at unclear doses is more marketing than mechanism. Nutrex is a legit sports-nutrition brand but this category is fundamentally weak. Would move to Standard 60 with either a clean sleep formula OR a fat burner, not both.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
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Nutrex LIPO-6 NightTime, 30 Caps is a product from PoorBoySupplements.com, categorized under Sleep supplements & nutraceuticals in the Sleep Optimization vertical. It is scored on the Vyvata Scoring Framework — an independent 6-dimension rubric applied uniformly to every product Vyvata lists.
50/100 overall — Rejected tier (0–49 band). Per-dimension breakdown: Manufacturing 55, Formulation 50, Safety 50, Transparency 50, Sustainability 50, Evidence 45. Scored as of 2026-08-24.
Nutrex LIPO-6 NightTime is a 'sleep + weight loss' combo product — a category with essentially zero RCT support for the compound claim. Typically stacks melatonin, valerian, GABA, plus fat-burner actives. Combining sleep aids with metabolic actives at unclear doses is more marketing than mechanism. Nutrex is a legit sports-nutrition brand but this category is fundamentally weak. Would move to Standard 60 with either a clean sleep formula OR a fat burner, not both.
Strongest: Manufacturing at 55/100 (third-party testing, GMP compliance, and facility audit status) and Formulation at 50/100 (dose adequacy, bioavailability form, and ingredient redundancy). Weakest: Sustainability at 50/100 (sourcing practices, packaging, and corporate practice) and Evidence at 45/100 (quality of published RCT support for the active ingredients at the label dose). All six dimensions feed the overall Vyvata score; a weakness on any one dimension pulls the overall down proportionally.
No third-party certifications (NSF, USP, ConsumerLab, or equivalent) were on record at the time of scoring. This affects the Manufacturing dimension score. The manufacturer may test internally or have obtained certification more recently — check the current product label for the most up-to-date information.
Would move to Standard 60 with either a clean sleep formula OR a fat burner, not both.
The top-ranked sleep supplements & nutraceuticals product in the Vyvata catalog is currently Ortho Molecular Products Botanicalm PM 30 Capsules at 73/100. See the full ranked list of 62 scored products in this subcategory at https://vyvata.com/pages/best-sleep-supplements-and-nutraceuticals-ranked.
The Vyvata Scoring Framework rates every listed product 0–100 across six dimensions: Evidence, Formulation, Manufacturing, Safety, Transparency, and Sustainability. Tier bands: Elite 85–100 (top-tier evidence + formulation + manufacturing), Verified 70–84 (strong on most dimensions), Standard 50–69 (solid but with weaknesses called out), Rejected 0–49 (specific failures documented). Rejected products remain listed with reasons. Full methodology at https://vyvata.com/pages/methodology.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. For customer reviews and community discussion, search external platforms directly: Amazon (https://www.amazon.com/s?k=PoorBoySupplements.com%20Nutrex%20LIPO-6%20NightTime%2C%2030%20Caps),Google(https://www.google.com/search?q=PoorBoySupplements.com%20Nutrex%20LIPO-6%20NightTime%2C%2030%20Caps+reviews),Reddit(https://www.reddit.com/search/?q=PoorBoySupplements.com%20Nutrex%20LIPO-6%20NightTime%2C%2030%20Caps%20review),andTrustpilot(https://www.trustpilot.com/search?query=PoorBoySupplements.com%20Nutrex%20LIPO-6%20NightTime%2C%2030%20Caps).Vyvatadoesnotaggregate,republish,orlicensethosethird-partyreviews.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
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Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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