Optimum Nutrition
THE BIOHACKING STANDARD
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NusaPure Pterostilbene at 250 mg per capsule delivers a dose within the studied range. Pterostilbene is a dimethylated analogue of resveratrol found in blueberries, with better oral bioavailability (~80% vs ~2% for resveratrol per Kapetanovic 2011) and longer plasma half-life. The most-cited human clinical trial is Riche 2013 (Nutr Res) which tested pterostilbene at 125 mg twice daily (250 mg/day) or 50 mg twice daily for 6-8 weeks and observed reductions in LDL cholesterol, blood pressure, and body weight but ALSO an increase in total cholesterol at the higher dose. McCormack 2013 reviewed pterostilbene's mechanism (Sirt1 activation, anti-inflammatory, anti-oxidant). Pterostilbene is a defensible longevity-adjacent supplement with a small but real human dataset at exactly the 250 mg/day dose this product delivers. Held in Standard by evidence-base still being early-stage, no branded standardization discussion, and no third-party purity COA.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
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