Optimum Nutrition
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Celery seed (Apium graveolens) is traditionally used as a diuretic and for gout via 3-n-butylphthalide (3nB) content; modern human evidence is limited (Madhavi et al. 2013 small hypertension trial). This 375mg of a 10:1 extract equates to about 3.75g raw-seed equivalent but is not standardized to 3nB or phthalide percentage. Salicylate cross-reactivity in aspirin-sensitive individuals should be noted. Would move to Verified 70+ with standardized 3nB content and identity testing.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
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NusaPure Celery Seed Capsules 10:1 Extract, 375 mg, 240 Veggie Caps, Non-GMO, Vegan is a product from NusaPure, categorized under Cardiovascular & heart health in the Supplements vertical. It is scored on the Vyvata Scoring Framework — an independent 6-dimension rubric applied uniformly to every product Vyvata lists.
60/100 overall — Standard tier (50–69 band). Per-dimension breakdown: Safety 65, Transparency 65, Formulation 60, Evidence 58, Manufacturing 55, Sustainability 50. Scored as of 2026-08-24.
Celery seed (Apium graveolens) is traditionally used as a diuretic and for gout via 3-n-butylphthalide (3nB) content; modern human evidence is limited (Madhavi et al. 2013 small hypertension trial). This 375mg of a 10:1 extract equates to about 3.75g raw-seed equivalent but is not standardized to 3nB or phthalide percentage. Salicylate cross-reactivity in aspirin-sensitive individuals should be noted. Would move to Verified 70+ with standardized 3nB content and identity testing.
Strongest: Safety at 65/100 (adverse-event profile, interaction risk, and dose ceiling) and Transparency at 65/100 (dose disclosure vs proprietary blends, and honesty of marketing claims). Weakest: Manufacturing at 55/100 (third-party testing, GMP compliance, and facility audit status) and Sustainability at 50/100 (sourcing practices, packaging, and corporate practice). All six dimensions feed the overall Vyvata score; a weakness on any one dimension pulls the overall down proportionally.
No third-party certifications (NSF, USP, ConsumerLab, or equivalent) were on record at the time of scoring. This affects the Manufacturing dimension score. The manufacturer may test internally or have obtained certification more recently — check the current product label for the most up-to-date information.
Would move to Verified 70+ with standardized 3nB content and identity testing.
The top-ranked cardiovascular & heart health product in the Vyvata catalog is currently Nordic Naturals Ultimate Omega 2X – High-Potency Fish Oil | 2150 mg EPA & DHA | Lemon Flavor, 120 Softgels at 87/100. See the full ranked list of 345 scored products in this subcategory at https://vyvata.com/pages/best-cardiovascular-and-heart-health-supplements-ranked.
The Vyvata Scoring Framework rates every listed product 0–100 across six dimensions: Evidence, Formulation, Manufacturing, Safety, Transparency, and Sustainability. Tier bands: Elite 85–100 (top-tier evidence + formulation + manufacturing), Verified 70–84 (strong on most dimensions), Standard 50–69 (solid but with weaknesses called out), Rejected 0–49 (specific failures documented). Rejected products remain listed with reasons. Full methodology at https://vyvata.com/pages/methodology.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. For customer reviews and community discussion, search external platforms directly: Amazon (https://www.amazon.com/s?k=NusaPure%20NusaPure%20Celery%20Seed%20Capsules%2010%3A1%20Extract%2C%20375%20mg%2C%20240%20Veggie%20Caps%2C%20Non-GMO%2C%20Vegan),Google(https://www.google.com/search?q=NusaPure%20NusaPure%20Celery%20Seed%20Capsules%2010%3A1%20Extract%2C%20375%20mg%2C%20240%20Veggie%20Caps%2C%20Non-GMO%2C%20Vegan+reviews),Reddit(https://www.reddit.com/search/?q=NusaPure%20NusaPure%20Celery%20Seed%20Capsules%2010%3A1%20Extract%2C%20375%20mg%2C%20240%20Veggie%20Caps%2C%20Non-GMO%2C%20Vegan%20review),andTrustpilot(https://www.trustpilot.com/search?query=NusaPure%20NusaPure%20Celery%20Seed%20Capsules%2010%3A1%20Extract%2C%20375%20mg%2C%20240%20Veggie%20Caps%2C%20Non-GMO%2C%20Vegan).Vyvatadoesnotaggregate,republish,orlicensethosethird-partyreviews.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
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Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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