Nature Made Super B Energy Complex Softgels - 60ct

Six-dimension breakdown

Why this scored 64/100

Nature Made Super B Energy Complex is a standard B-vitamin softgel from Pharmavite's flagship consumer supplement brand — the mass-retail US brand most consistently associated with USP verification, which independently confirms label-vs-actual dose accuracy, purity limits, and dissolution. The B-complex composition typically covers the eight B vitamins (thiamine, riboflavin, niacin, pantothenic acid, B6, biotin, folate, B12) plus vitamin C. B vitamins are legitimate essential micronutrients required for energy metabolism (mitochondrial substrate metabolism, one-carbon transfer, neurotransmitter synthesis) — the 'energy metabolism support' language matches the actual biochemistry rather than being an unverified performance claim. What caps the score: for adults without documented B-vitamin deficiency (which is relatively uncommon in the US outside of specific populations — vegans/vegetarians for B12, older adults for B12, alcohol-use-disorder for thiamine and folate, pregnancy for folate), B-complex supplementation does not produce a subjective energy boost — the marketing implication that B vitamins provide caffeine-like alertness is misleading. Manufacturing and third-party quality verification are the strongest dimensions; transparency is capped by aggregate USP verification rather than per-lot public COAs. Standard-tier mass-retail B-complex — appropriate for documented deficiency or targeted populations, oversold for the general population.

Evidence & sources

The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.

Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.

How to read the Evidence dimension

• 80–100: Multiple double-blind RCTs in indexed journals directly testing this product OR the exact ingredients at the exact dose.
• 60–79: Single double-blind RCT + supporting ingredient literature at the studied dose.
• 40–59: Open-label trials + ingredient literature; no product-specific double-blind evidence.
• 20–39: Ingredient literature only; no product-specific trials or trials in predatory venues.
• 0–19: No credible evidence base or unverifiable claims.

FAQ data has not been generated for this product yet. See the site FAQ for general questions.

Customer reviews

All the data we have on this product

Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.

VSF score

64 / 100

Tier

Standard

Category

Supplements

Subcategory

vitamins micronutrients

Last scored

August 29, 2026

Third-party certifications

None on record at time of scoring

Vendor

Pasteur Pharmacy

Product type

Vitamins & Supplements

Tags

Pasteur Pharmacy, Shopify Collective

Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.