Optimum Nutrition
THE BIOHACKING STANDARD
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Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
Creatine monohydrate is the most-studied sports supplement in existence — over 1,000 published trials since the mid-1990s document reliable effects on strength, power output, muscle mass, and (increasingly) cognitive performance under stress or sleep deprivation. Dosing consensus is well-established: 3-5g/day (no loading required, though a 20g/day loading phase for 5-7 days accelerates saturation). Creatine monohydrate is the reference form — no other form (HCl, ethyl ester, magnesium chelate, kre-alkalyn) has demonstrated superior clinical outcomes to plain monohydrate at fair comparison. Safety profile is excellent: no evidence of renal harm in healthy adults across long-term trials, no evidence of hair loss (the DHT rumor traces to a single small rugby-player study that has never replicated). "Micronized" refers to particle-size reduction that improves powder dispersion in water without changing the molecule. This product's core substance is essentially unimpeachable. The 71 score reflects that the substance itself is best-in-class evidence, tempered by the absence of a visible Creapure branded ingredient badge (the German-manufactured, chromatographically-verified creatine standard used by top-tier brands like Momentous and Thorne), absence of visible NSF Certified for Sport testing, and undisclosed per-scoop dosing at the title level.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
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Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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