Optimum Nutrition
THE BIOHACKING STANDARD
Welcome to our store
Couldn't load pickup availability
Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
L-glutamine is the most abundant free amino acid in human plasma and skeletal muscle, and it is a conditionally essential amino acid — becoming genuinely essential during severe catabolic stress (major surgery, sepsis, burns), where clinical enteral or parenteral glutamine supplementation has evidence for reduced infections and shorter ICU stays. In the general sports-nutrition context, however, oral glutamine's story is much weaker: healthy trained athletes with adequate protein intake show minimal-to-no benefit for muscle protein synthesis, recovery, or immune function from adding oral glutamine on top of a normal high-protein diet. Glutamine's utility in gut-lining support (leaky gut, IBD) is more promising, and it is often recommended at 5-10g/day for gut integrity in functional-medicine contexts. MRI Performance Glutamine at 1000g (2.2 lb bulk powder) is a real single-ingredient product at a fair price. Standard tier: legitimate but not category-leading — the supplement itself is honest, but the underlying evidence for the sports-recovery framing is weak in trained athletes.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

Optimum Nutrition
Onnit
WOW MD LLC
Prevagen
Find Your Protocol
A few quick questions about your goals and current concerns. We'll build a tailored protocol — a Basics list of essentials plus a comprehensive Biohackers list — across all Vyvata categories.
No signup required · Your protocol is private to you