Motility PRO® 60ct

Six-dimension breakdown

Why this scored 68/100

Motility PRO is Ortho Molecular's gastric motility formula built around a patented combination of ginger (Zingiber officinale) extract and artichoke leaf extract (Cynara cardunculus) — the branded ingredient is Prodigest, a specific clinically-studied ginger/artichoke combination developed by Indena and tested in placebo-controlled trials for functional dyspepsia and delayed gastric emptying. Giacosa 2015 in a randomized double-blind placebo-controlled trial showed significant improvement in functional dyspepsia symptoms with Prodigest over four weeks. The clinical trial evidence is real, the dose in the commercial formula matches the tested dose, and the mechanism (ginger's prokinetic effect via 5-HT3 antagonism and cholinergic activation, artichoke's cynarin-mediated bile and digestive secretion) is well-characterized. Ortho Molecular's product page explicitly references "clinically proven dose," which is unusual and accurate marketing language for a supplement — most brands overstate but here the reference is grounded. This is one of the better-evidenced Ortho Molecular products in this batch. Standard tier at the upper end reflects strong single-purpose formulation on a specific patented ingredient with real RCT support, held below Verified only by the multi-active blend structure and absent explicit third-party assay disclosure.

Evidence & sources

The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.

Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.

How to read the Evidence dimension

• 80–100: Multiple double-blind RCTs in indexed journals directly testing this product OR the exact ingredients at the exact dose.
• 60–79: Single double-blind RCT + supporting ingredient literature at the studied dose.
• 40–59: Open-label trials + ingredient literature; no product-specific double-blind evidence.
• 20–39: Ingredient literature only; no product-specific trials or trials in predatory venues.
• 0–19: No credible evidence base or unverifiable claims.

FAQ data has not been generated for this product yet. See the site FAQ for general questions.

Customer reviews

All the data we have on this product

Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.

VSF score

68 / 100

Tier

Standard

Category

Supplements

Subcategory

gut digestive

Last scored

August 30, 2026

Third-party certifications

None on record at time of scoring

Vendor

O Body + Wellness

Tags

O Body + Wellness, Shopify Collective

Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.