Optimum Nutrition
THE BIOHACKING STANDARD
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Mother Earth's Lugol's Iodine Plus delivers iodine in the Lugol's format (both molecular iodine I2 and iodide I-). Iodine is genuinely essential for thyroid hormone synthesis, and modest supplementation makes sense for populations with documented deficiency (pregnancy, restrictive diets that avoid iodized salt, seafood, and dairy). However, the framing that 'up to 90% of Americans may be deficient in iodine' overstates the evidence — surveillance data from NHANES shows median urinary iodine in the sufficient range for the US population, with pregnant women being the identifiable gap. High-dose Lugol's iodine supplementation (5-50 mg elemental iodine daily) exceeds the RDA (150 mcg for adults) by 30-300x and is a known trigger for both hyperthyroidism (Jod-Basedow phenomenon) and hypothyroidism (Wolff-Chaikoff effect) in susceptible individuals with autoimmune thyroid predisposition. The 'Iodine Plus' framing is common in the alternative-health iodine advocacy community but rests on contested claims about pharmacologic iodine's role in health. Safety score is reduced due to real thyroid-disruption risk. Standard-tier for the underlying nutrient; caution warranted on high-dose Lugol's specifically.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
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