Optimum Nutrition
THE BIOHACKING STANDARD
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Metabolic Nutrition NAD MAX in 30-capsule count is structurally underdosed for the ingredient category it represents. NAD+ precursor supplementation (NMN or NR — Metabolic Nutrition does not clearly disclose which) has Grade B evidence for raising blood NAD+ metabolite pools at doses of 250-500 mg/day taken consistently. A 30-capsule package is a 30-day supply at 1 capsule/day — for this to deliver an evidence-relevant dose the single capsule would need to contain 250+ mg NMN or NR. Metabolic Nutrition does not prominently document that per-capsule dose, and the '30 capsules' framing strongly suggests either underdosing or a very short supply run. Autofail on sub_therapeutic_dose for a longevity-marketed product with a category-inadequate per-serving amount. Rejected tier.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
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Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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