Optimum Nutrition
THE BIOHACKING STANDARD
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Neurogan Health Liposomal Fisetin Capsules use a phospholipid-based liposomal delivery system intended to improve fisetin's notoriously poor oral bioavailability (~2% for free fisetin). Liposomal encapsulation is a defensible bioavailability strategy — Kadari 2017 and other PK studies show 2-4x improvements in plasma AUC for liposomal flavonoids vs. free-form powders — though independent head-to-head PK comparisons for this specific product are not published. Per-capsule fisetin dose is not clearly stated in the description reviewed, which is a transparency gap. The daily-dose regimen (1-2 caps/day) does not match the intermittent senolytic protocol being studied in the Mayo Clinic AFFIRM trial. Standard tier — legitimately-designed bioavailability format that partly addresses fisetin's PK limitations, held back by dose transparency and by the general early-stage human evidence for fisetin itself.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
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