Optimum Nutrition
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Lion's Mane Mushroom
Lion's Mane Mushroom
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Regular price
$24.99 USD
Regular price
Sale price
$24.99 USD
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The full picture
Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
60/100
Standard
Six-dimension breakdown
Evidence
55
Formulation
62
Manufacturing
60
Safety
65
Transparency
62
Sustainability
58
Why this scored 60/100
Midwest Method Lion's Mane is single-ingredient organic Hericium erinaceus using both fruiting body AND mycelium, standardized to 40% polysaccharides, delivering approximately 400 mg per capsule. The fruiting-body-plus-mycelium approach is common in mid-tier mushroom supplements; premium brands (Real Mushrooms, Nootropics Depot) generally use fruiting-body only and standardize to beta-glucans rather than total polysaccharides because total-polysaccharide standardization includes starch/dextrin from grain substrate that mycelium is grown on and inflates the marker without adding bioactive fungal content. The published cognitive-support evidence for lion's mane (Mori 2009 at 3 g/day in adults with mild cognitive impairment; Saitsu 2019 at 3.2 g/day) used fruiting-body powder at gram-scale doses. Midwest Method's per-capsule 400 mg is well below these trial doses even at a two-capsule serving. Honest single-ingredient labeling and standardization disclosure hold it in Standard tier; the polysaccharide-vs-beta-glucan choice and sub-trial dose keep it out of Verified.
Last scored: Full rubric →
Evidence & sources
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
How to read the Evidence dimension
- 80–100: Multiple double-blind RCTs in indexed journals directly testing this product OR the exact ingredients at the exact dose.
- 60–79: Single double-blind RCT + supporting ingredient literature at the studied dose.
- 40–59: Open-label trials + ingredient literature; no product-specific double-blind evidence.
- 20–39: Ingredient literature only; no product-specific trials or trials in predatory venues.
- 0–19: No credible evidence base or unverifiable claims.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
Customer reviews
Reviews on other platforms
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
All the data we have on this product
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
- VSF score
- 60 / 100
- Tier
- Standard
- Category
- Supplements
- Subcategory
- cognitive nootropics
- Last scored
- Third-party certifications
- None on record at time of scoring
- Vendor
- Midwest Method
- Product type
- Mushroom Products
- Tags
- Midwest Method, Shopify Collective
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.
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