Optimum Nutrition
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Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
HepatoCORE is an Ortho Molecular Products liver-support formula — OMP is a practitioner-channel-only brand with strong cGMP, batch testing, and physician-facing formulation standards. The typical HepatoCORE stack (milk thistle silymarin, NAC, alpha-lipoic acid, curcumin, selenium, taurine) has legitimate hepatoprotective evidence: silymarin for NAFLD markers (Aller 2015), NAC for acetaminophen and general hepatocyte support, and curcumin for liver enzyme reduction (Panahi 2016). It sits below Elite mainly because the formula is a multi-ingredient combo rather than a single-active mono-formula with a hard RCT anchor, and the retail listing lacks direct COA transparency. Would move to Elite 85+ with published per-ingredient standardization and third-party lot testing available to the consumer.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
Auto-generated from Vyvata's scoring data for this product. For general questions about the store (shipping, returns, wholesale), see the site FAQ.
HepatoCORE 60ct is a product from O Body + Wellness, categorized under Immune health & antioxidants in the Supplements vertical. It is scored on the Vyvata Scoring Framework — an independent 6-dimension rubric applied uniformly to every product Vyvata lists.
72/100 overall — Verified tier (70–84 band). Per-dimension breakdown: Manufacturing 78, Formulation 72, Safety 72, Transparency 70, Evidence 68, Sustainability 60. Scored as of 2026-08-24.
HepatoCORE is an Ortho Molecular Products liver-support formula — OMP is a practitioner-channel-only brand with strong cGMP, batch testing, and physician-facing formulation standards. The typical HepatoCORE stack (milk thistle silymarin, NAC, alpha-lipoic acid, curcumin, selenium, taurine) has legitimate hepatoprotective evidence: silymarin for NAFLD markers (Aller 2015), NAC for acetaminophen and general hepatocyte support, and curcumin for liver enzyme reduction (Panahi 2016). It sits below Elite mainly because the formula is a multi-ingredient combo rather than a single-active mono-formula with a hard RCT anchor, and the retail listing lacks direct COA transparency. Would move to Elite 85+ with published per-ingredient standardization and third-party lot testing available to the consumer.
Strongest: Manufacturing at 78/100 (third-party testing, GMP compliance, and facility audit status) and Formulation at 72/100 (dose adequacy, bioavailability form, and ingredient redundancy). Weakest: Evidence at 68/100 (quality of published RCT support for the active ingredients at the label dose) and Sustainability at 60/100 (sourcing practices, packaging, and corporate practice). All six dimensions feed the overall Vyvata score; a weakness on any one dimension pulls the overall down proportionally.
No third-party certifications (NSF, USP, ConsumerLab, or equivalent) were on record at the time of scoring. This affects the Manufacturing dimension score. The manufacturer may test internally or have obtained certification more recently — check the current product label for the most up-to-date information.
Would move to Elite 85+ with published per-ingredient standardization and third-party lot testing available to the consumer.
The top-ranked immune health & antioxidants product in the Vyvata catalog is currently PreserVision AREDS 2 Eye Vitamins, 210 Soft gels at 77/100. See the full ranked list of 590 scored products in this subcategory at https://vyvata.com/pages/best-immune-health-and-antioxidants-supplements-ranked.
The Vyvata Scoring Framework rates every listed product 0–100 across six dimensions: Evidence, Formulation, Manufacturing, Safety, Transparency, and Sustainability. Tier bands: Elite 85–100 (top-tier evidence + formulation + manufacturing), Verified 70–84 (strong on most dimensions), Standard 50–69 (solid but with weaknesses called out), Rejected 0–49 (specific failures documented). Rejected products remain listed with reasons. Full methodology at https://vyvata.com/pages/methodology.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. For customer reviews and community discussion, search external platforms directly: Amazon (https://www.amazon.com/s?k=O%20Body%20%2B%20Wellness%20HepatoCORE%2060ct),Google(https://www.google.com/search?q=O%20Body%20%2B%20Wellness%20HepatoCORE%2060ct+reviews),Reddit(https://www.reddit.com/search/?q=O%20Body%20%2B%20Wellness%20HepatoCORE%2060ct%20review),andTrustpilot(https://www.trustpilot.com/search?query=O%20Body%20%2B%20Wellness%20HepatoCORE%2060ct).Vyvatadoesnotaggregate,republish,orlicensethosethird-partyreviews.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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