Optimum Nutrition
THE BIOHACKING STANDARD
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Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
Happy Nerve is a Prairie Star Botanicals multi-herb proprietary-blend tincture containing Happy Nerve (proprietary blend of Skullcap, California Poppy, Wood Betony, Passionflower, Linden, Hops, Lemon Balm, Mugwort), positioned for nervine calming. Passionflower and hops have small anxiolytic and sleep-supportive RCT evidence at specific doses. Without per-herb dosing this cannot transfer. Mugwort contains thujone with real safety flags. Skullcap has hepatotoxicity case reports (some due to American Skullcap adulteration). Mugwort thujone (not for pregnancy, potential abortifacient); skullcap hepatotoxicity signal; proprietary-blend dosing risk. Prairie Star Botanicals is a small US herbalist line built around locally-harvested (where possible) single-herb liquid extracts. The single-ingredient tincture format is honest — you can see exactly what you're taking. What Prairie Star Botanicals does NOT publish at the product level: third-party certificates of analysis, per-lot heavy-metal or microbial testing, herb-to-menstruum extraction ratios, or standardized marker-compound percentages. That opacity is what caps most of the line at Standard-tier or below in Vyvata's rubric even when the herb itself has real evidence.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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