Optimum Nutrition
THE BIOHACKING STANDARD
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Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
A women's DIM (diindolylmethane) product explicitly self-described as a 'proprietary blend.' DIM as a single ingredient has a real evidence base for oestrogen metabolism support (shifting the 2-hydroxyestrone / 16-hydroxyestrone ratio toward 2-OH), which is a plausible mechanism for premenstrual symptom and hormone-clearance support. If this were a clearly-dosed DIM product at 100-200 mg, it could score Standard. But calling it a 'proprietary blend' by name — Happy DIM is 'a proprietary blend formulated by Dr Jeff Butterworth' — tells the reviewer that the exact DIM milligram amount and any other actives are not disclosed. Under the Zero-Assumption Rule and the proprietary_blend_hides_dose autofail rule, undisclosed multi-ingredient formulations forfeit tier eligibility. Auto-fail applied.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
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Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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