Optimum Nutrition
THE BIOHACKING STANDARD
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Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
NYC Herbs Fadogia Agrestis is a single-ingredient SKU where the ingredient itself is the problem — Fadogia agrestis has zero human RCTs, and the sole preclinical support (Yakubu 2005 in rats) also documented dose-dependent testicular toxicity, kidney dysfunction, and reduced sperm count. 'Vitality & Stamina Support' invokes T-boosting/libido claims without any human evidence base. Even with clean dose disclosure (a modest transparency positive over blended SKUs), an ingredient with no human data and a known rodent safety signal cannot pass Standard tier in a transparency-first rubric. Autofailed under unverified_medical_claim. Would not be reconsidered above Rejected until published human safety and efficacy trials exist.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
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Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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