Optimum Nutrition
THE BIOHACKING STANDARD
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Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
Dragon Pharma VENOM is a very-high-stimulant pre-workout carrying 400 mg of caffeine per serving, marketed for experienced users only. Even taking the brand's marketing at face value on 'clinically dosed performance ingredients,' the 400 mg single-scoop caffeine load is the primary problem: it hits FDA's total-day guidance in a single dose, leaves no room for coffee, a stacked pump product, or a second scoop, and pushes cardiovascular and sleep-disruption risk into a range where Vyvata will not list. That threshold applies even when the rest of the formula is competent. The reformulated (New) VENOM improved dose disclosure over the earlier prop-blend version, and Dragon Pharma operates cGMP-registered US contract manufacturing, but published per-lot COAs and third-party sport certification (Informed Sport / NSF Certified for Sport) are not standard on this line. Combined with the caffeine load, and typical secondary stimulants in the category (theobromine, higenamine or synephrine analogs common in 400 mg-caffeine pre-workouts) the safety profile is a hard gate. Rejected on safety grounds — not because the ingredients are novel or unstudied, but because the total stimulant load at a single serving crosses the guardrail we set for a home-use consumer product. Would become listable at Standard 55-62 with a caffeine cap at ~300 mg per scoop, dropping any synephrine/higenamine-class secondary stimulants, and adding Informed Sport certification.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
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Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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