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Deep Rest & Stress Relief - Featuring KaraCalm
Deep Rest & Stress Relief - Featuring KaraCalm
No reviews
No reviews
Regular price
$18.69 USD
Regular price
Sale price
$18.69 USD
Shipping calculated at checkout.
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The full picture
Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
62/100
Standard
Six-dimension breakdown
Evidence
58
Formulation
62
Manufacturing
62
Safety
65
Transparency
62
Sustainability
50
Why this scored 62/100
KaraCalm (branded Sceletium tortuosum / kanna extract) has small trials suggesting anxiolytic and stress-cortisol effects (Chiu 2014 at 25 mg Zembrin). Naming the branded ingredient at label is a formulation positive. Sceletium interacts with MAOI/SSRI medications — this needs explicit drug-interaction disclosure that isn't visible from the title. Would move to Verified 70+ with dose matched to the Zembrin/KaraCalm trial protocols and pharmacotherapy caution stated at label.
Last scored: Full rubric →
Evidence & sources
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
How to read the Evidence dimension
- 80–100: Multiple double-blind RCTs in indexed journals directly testing this product OR the exact ingredients at the exact dose.
- 60–79: Single double-blind RCT + supporting ingredient literature at the studied dose.
- 40–59: Open-label trials + ingredient literature; no product-specific double-blind evidence.
- 20–39: Ingredient literature only; no product-specific trials or trials in predatory venues.
- 0–19: No credible evidence base or unverifiable claims.
Frequently asked questions
Auto-generated from Vyvata's scoring data for this product. For general questions about the store (shipping, returns, wholesale), see the site FAQ.
What is Deep Rest & Stress Relief - Featuring KaraCalm?
Deep Rest & Stress Relief - Featuring KaraCalm, categorized under Stress, mood & mental wellness in the Supplements vertical. It is scored on the Vyvata Scoring Framework — an independent 6-dimension rubric applied uniformly to every product Vyvata lists.
How does Deep Rest & Stress Relief - Featuring KaraCalm score on the Vyvata rubric?
62/100 overall — Standard tier (50–69 band). Per-dimension breakdown: Safety 65, Formulation 62, Manufacturing 62, Transparency 62, Evidence 58, Sustainability 50. Scored as of 2026-08-24.
Why did Deep Rest & Stress Relief - Featuring KaraCalm score in the Standard tier?
KaraCalm (branded Sceletium tortuosum / kanna extract) has small trials suggesting anxiolytic and stress-cortisol effects (Chiu 2014 at 25 mg Zembrin). Naming the branded ingredient at label is a formulation positive. Sceletium interacts with MAOI/SSRI medications — this needs explicit drug-interaction disclosure that isn't visible from the title. Would move to Verified 70+ with dose matched to the Zembrin/KaraCalm trial protocols and pharmacotherapy caution stated at label.
What are the strongest and weakest aspects of this product?
Strongest: Safety at 65/100 (adverse-event profile, interaction risk, and dose ceiling) and Formulation at 62/100 (dose adequacy, bioavailability form, and ingredient redundancy). Weakest: Evidence at 58/100 (quality of published RCT support for the active ingredients at the label dose) and Sustainability at 50/100 (sourcing practices, packaging, and corporate practice). All six dimensions feed the overall Vyvata score; a weakness on any one dimension pulls the overall down proportionally.
Is Deep Rest & Stress Relief - Featuring KaraCalm third-party tested?
No third-party certifications (NSF, USP, ConsumerLab, or equivalent) were on record at the time of scoring. This affects the Manufacturing dimension score. The manufacturer may test internally or have obtained certification more recently — check the current product label for the most up-to-date information.
What would move Deep Rest & Stress Relief - Featuring KaraCalm to a higher tier?
Would move to Verified 70+ with dose matched to the Zembrin/KaraCalm trial protocols and pharmacotherapy caution stated at label.
Are there higher-scoring alternatives to Deep Rest & Stress Relief - Featuring KaraCalm?
The top-ranked stress, mood & mental wellness product in the Vyvata catalog is currently Momentous Sleep at 77/100. See the full ranked list of 247 scored products in this subcategory at https://vyvata.com/pages/best-stress-mood-and-mental-wellness-supplements-ranked.
What does the Vyvata score mean?
The Vyvata Scoring Framework rates every listed product 0–100 across six dimensions: Evidence, Formulation, Manufacturing, Safety, Transparency, and Sustainability. Tier bands: Elite 85–100 (top-tier evidence + formulation + manufacturing), Verified 70–84 (strong on most dimensions), Standard 50–69 (solid but with weaknesses called out), Rejected 0–49 (specific failures documented). Rejected products remain listed with reasons. Full methodology at https://vyvata.com/pages/methodology.
Where can I read customer reviews for Deep Rest & Stress Relief - Featuring KaraCalm?
The Vyvata score measures product integrity against a published rubric, not customer sentiment. For customer reviews and community discussion, search external platforms directly: Amazon (https://www.amazon.com/s?k=Deep%20Rest%20%26%20Stress%20Relief%20-%20Featuring%20KaraCalm),Google(https://www.google.com/search?q=Deep%20Rest%20%26%20Stress%20Relief%20-%20Featuring%20KaraCalm+reviews),Reddit(https://www.reddit.com/search/?q=Deep%20Rest%20%26%20Stress%20Relief%20-%20Featuring%20KaraCalm%20review),andTrustpilot(https://www.trustpilot.com/search?query=Deep%20Rest%20%26%20Stress%20Relief%20-%20Featuring%20KaraCalm).Vyvatadoesnotaggregate,republish,orlicensethosethird-partyreviews.
Customer reviews
Reviews on other platforms
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
All the data we have on this product
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
- VSF score
- 62 / 100
- Tier
- Standard
- Category
- Supplements
- Subcategory
- stress mood mental
- Last scored
- Third-party certifications
- None on record at time of scoring
- Vendor
- Swanson Vitamins
- Tags
- Shopify Collective, Swanson Vitamins
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.
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