Optimum Nutrition
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APACHE STAR Collagen Gummies pair hydrolyzed marine collagen peptides (from tilapia and cod, disclosed) with vitamin C, zinc, biotin, and vitamin E in an orange-flavored gummy taken as two gummies daily. The formulation choices are sensible: vitamin C is a required cofactor for endogenous collagen synthesis, biotin and zinc support keratin/skin turnover, and hydrolyzed peptides are the collagen form with the strongest human RCT evidence for skin elasticity and hydration (Choi 2019 meta-analysis, Bolke 2019 RCT). The two-gummy-per-day format constrains the achievable peptide dose — clinical trials showing skin benefits generally use 2.5-10 g of collagen peptides per day, and a two-gummy serving typically delivers 1-2.5 g, likely on the low end of clinically meaningful. Manufacturer disclosure of the fish source is a transparency positive; a full milligram-by-milligram Supplement Facts panel and lot COAs would move this into Verified territory. Solid Standard entry with a small-brand handicap.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
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