Optimum Nutrition
THE BIOHACKING STANDARD
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Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
A chromium concentrate disclosing 750 mcg per serving (375% DV). Dose disclosure is above average for this brand line and earns transparency credit. The dose itself is high — DV is 35 mcg (older 120 mcg for supplement labelling), and 750 mcg is well above the RDA-equivalent range while remaining below the toxicity threshold. Chromium's marginal essentiality (some authorities have questioned whether it's truly essential) and modest RCT evidence for type 2 diabetes and insulin sensitivity remain the underlying evidence context. Description mentions role in fat and cholesterol synthesis in the liver, which reflects older biochemical hypotheses more than confirmed clinical outcomes. Solid Standard on the strength of dose disclosure.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
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Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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