Optimum Nutrition
THE BIOHACKING STANDARD
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Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
Vitamin Patch Club 'Super8' B-Performance is a transdermal vitamin patch delivering all 8 essential B vitamins for cardiovascular support, metabolic burn, and energy. The core mechanism problem is that transdermal vitamin absorption has essentially no peer-reviewed bioavailability evidence for most water-soluble vitamins, including B-complex. The skin is designed to be a barrier — it evolved to keep foreign molecules out. Compounds that can cross skin efficiently are small (under ~500 Da), lipid-soluble, and often require permeation enhancers (like the skin-penetration drivers in transdermal nicotine or hormone patches). B vitamins are mostly water-soluble (except B12), typically well over 500 Da, and have essentially no clinical evidence of meaningful transdermal absorption despite marketing claims across the vitamin-patch industry. B12 is the one exception with limited pharmacokinetic support (Berlin 1968 injectable-vs-oral B12 studies; a 2019 open-label transdermal B12 patch study by Vitamin Patch Club vendors showed variable serum-level increases). Autofail on unverified_medical_claim for the 'cardio support, metabolic burn, energy' claims delivered by an unvalidated route. Not a category Vyvata endorses as-is.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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