ageLOC® Youth Anti-aging Supplement

Six-dimension breakdown

Why this scored 48/100

ageLOC Youth is Nu Skin's flagship 'anti-aging supplement' — the marketing claims 'the power to defy your age' and 'revitalize your aging defense mechanisms' via a proprietary formulation built on 'over a decade of research.' Product copy language ('defy your age', 'youth' as the product name, 'anti-aging supplement' as the category) triggers the unverified_medical_claim flag under the Vyvata rubric — no supplement, including this one, has RCT-outcome evidence for reversing or 'defying' aging as measured by validated biomarkers (DNA methylation clocks, telomere length, senescence markers, functional healthspan). The ingredient base is likely reasonable (Nu Skin's ageLOC line typically combines mixed carotenoids, polyphenols like resveratrol, sirtuin activators, and adaptogens) — individual ingredients may have Grade B-C evidence for narrower outcomes like reducing oxidative stress markers or supporting mitochondrial function. What triggers the Rejected status is the combination of (1) 'Youth' + 'Anti-aging' + 'defy your age' framing exceeding the actual evidence base for the specific formulation, (2) proprietary-blend positioning, and (3) MLM channel. This is the closest of the 17 SKUs to an autofail on unverified_medical_claim; scoring conservatively as Rejected 48 with the flag applied but not autofailing outright pending the label check on ingredient disclosure.

Evidence & sources

The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.

Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.

How to read the Evidence dimension

• 80–100: Multiple double-blind RCTs in indexed journals directly testing this product OR the exact ingredients at the exact dose.
• 60–79: Single double-blind RCT + supporting ingredient literature at the studied dose.
• 40–59: Open-label trials + ingredient literature; no product-specific double-blind evidence.
• 20–39: Ingredient literature only; no product-specific trials or trials in predatory venues.
• 0–19: No credible evidence base or unverifiable claims.

FAQ data has not been generated for this product yet. See the site FAQ for general questions.

Customer reviews

All the data we have on this product

Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.

VSF score

48 / 100

Tier

Rejected

Category

Supplements

Subcategory

longevity cellular

Last scored

August 29, 2026

Third-party certifications

None on record at time of scoring

Vendor

Leaders Beauty & Wellness

Tags

Leaders Beauty & Wellness, Shopify Collective

Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.