Optimum Nutrition
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5% Nutrition Stage Ready is a diuretic supplement marketed as 'the most powerful diuretic on the market' using dandelion root, shavegrass, and uva ursi. The product is specifically positioned for competitive bodybuilders trying to reduce subcutaneous water in the final 3-7 days before a stage appearance. Herbal diuretics at high doses cause meaningful diuresis; they also cause electrolyte imbalances (especially potassium depletion), acute hypotension, muscle cramps, and in extreme cases cardiac arrhythmias. The bodybuilding-industry history includes documented deaths from stage-prep diuretic protocols (Andreas Munzer 1996 is the most cited case, from prescription diuretics; but herbal-diuretic-adjacent deaths and hospitalizations have been reported). The Rich Piana history the marketing invokes is itself a red flag — Piana died in 2017 at 46, and while cause of death was heart-related without direct diuretic attribution, the bodybuilding-industry pattern of stage-prep dehydration protocols correlates with cardiovascular events. Autofailed on unverified_medical_claim (the 'stage ready' positioning is a competitive-athletic-prep claim that oversells modest herbal diuretics' effects) and safety concerns for the target-user protocol. Not listable in current form.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
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