Optimum Nutrition
1
/
of
2
5% Nutrition Joint Defender - 200 Capsules
5% Nutrition Joint Defender - 200 Capsules
No reviews
No reviews
Regular price
$40.99 USD
Regular price
Sale price
$40.99 USD
Shipping calculated at checkout.
Quantity
Couldn't load pickup availability
The full picture
Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
58/100
Standard
Six-dimension breakdown
Evidence
55
Formulation
60
Manufacturing
55
Safety
68
Transparency
55
Sustainability
45
Why this scored 58/100
5% Nutrition Joint Defender combines glucosamine, chondroitin sulfate, MSM, and KollaGen II-xs (undenatured type II collagen at 2 g). The joint-support category has mixed RCT evidence: glucosamine plus chondroitin has been studied extensively (GAIT trial and follow-ups) with modest benefit for moderate-to-severe osteoarthritis pain and minimal benefit for mild osteoarthritis or general joint 'maintenance' in healthy adults. MSM has some RCT support for OA pain at 3-6 g/day. Undenatured type II collagen (UC-II) has emerging RCT support at 40 mg/day (roughly 1/50th the 2 g dose 5% Nutrition uses — the higher dose is not necessarily better because the immunomodulatory mechanism has a threshold effect). 5% Nutrition's formulation covers the major joint ingredients but at doses that may miss ideal thresholds. Transparency and manufacturing documentation is below top tier. Standard-tier joint product for someone with mild-to-moderate joint discomfort; better-documented single-ingredient options exist.
Last scored: Full rubric →
Evidence & sources
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
How to read the Evidence dimension
- 80–100: Multiple double-blind RCTs in indexed journals directly testing this product OR the exact ingredients at the exact dose.
- 60–79: Single double-blind RCT + supporting ingredient literature at the studied dose.
- 40–59: Open-label trials + ingredient literature; no product-specific double-blind evidence.
- 20–39: Ingredient literature only; no product-specific trials or trials in predatory venues.
- 0–19: No credible evidence base or unverifiable claims.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
Customer reviews
Reviews on other platforms
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
All the data we have on this product
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
- VSF score
- 58 / 100
- Tier
- Standard
- Category
- Supplements
- Subcategory
- longevity cellular
- Last scored
- Third-party certifications
- None on record at time of scoring
- Vendor
- Ultimate Sport Nutrition
- Product type
- Repair & Recovery
- Tags
- Shopify Collective, Ultimate Sport Nutrition
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.
Share
