Optimum Nutrition
1
/
of
1
21st Century GLP-1 60 Vegetarian Capsules
21st Century GLP-1 60 Vegetarian Capsules
No reviews
No reviews
Regular price
$22.99 USD
Regular price
Sale price
$22.99 USD
Shipping calculated at checkout.
Quantity
Couldn't load pickup availability
The full picture
Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
38/100
Rejected
Six-dimension breakdown
Evidence
32
Formulation
45
Manufacturing
55
Safety
55
Transparency
40
Sustainability
45
Why this scored 38/100
21st Century 'GLP-1' branded supplement. Auto-fail: unverified_medical_claim. 'GLP-1' is the specific active pharmaceutical mechanism of prescription drugs like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro) — these are injectable peptides that directly agonize the glucagon-like peptide-1 receptor. NO oral supplement can produce meaningful GLP-1 receptor agonism at supplement doses — the peptide-mimetic action requires the specific molecular structure of the pharmaceutical drugs. Using 'GLP-1' as a product name implies mechanistic equivalence to Ozempic/Wegovy that isn't supported by any RCT evidence. This category (OTC 'GLP-1 alternatives') is under active FTC scrutiny for deceptive marketing. Whatever herbal/nutrient combination is inside the capsule may have its own modest evidence for glucose/appetite modulation — but the 'GLP-1' branding misrepresents the mechanism. Would move to Standard 55+ with removal of 'GLP-1' framing + honest ingredient-specific positioning.
Auto-fail rule triggered: Unverified medical claim.
A specific medical or physiological benefit claim on the label or marketing is not supported by published clinical evidence in humans. Distinct from disease claims — this covers narrower physiological claims (e.g. 'increases NAD+ by X%', 'boosts immunity') without published RCT support at the actual product dose and formulation. See the full rubric →
Last scored: Full rubric →
Evidence & sources
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
How to read the Evidence dimension
- 80–100: Multiple double-blind RCTs in indexed journals directly testing this product OR the exact ingredients at the exact dose.
- 60–79: Single double-blind RCT + supporting ingredient literature at the studied dose.
- 40–59: Open-label trials + ingredient literature; no product-specific double-blind evidence.
- 20–39: Ingredient literature only; no product-specific trials or trials in predatory venues.
- 0–19: No credible evidence base or unverifiable claims.
Frequently asked questions
Auto-generated from Vyvata's scoring data for this product. For general questions about the store (shipping, returns, wholesale), see the site FAQ.
What is 21st Century GLP-1 60 Vegetarian Capsules?
21st Century GLP-1 60 Vegetarian Capsules, categorized under Weight management & metabolic health in the Supplements vertical. It is scored on the Vyvata Scoring Framework — an independent 6-dimension rubric applied uniformly to every product Vyvata lists.
How does 21st Century GLP-1 60 Vegetarian Capsules score on the Vyvata rubric?
38/100 overall — Rejected tier (0–49 band). Per-dimension breakdown: Manufacturing 55, Safety 55, Formulation 45, Sustainability 45, Transparency 40, Evidence 32. Scored as of 2026-08-24.
Why did 21st Century GLP-1 60 Vegetarian Capsules score in the Rejected tier?
21st Century 'GLP-1' branded supplement. Auto-fail: unverified_medical_claim. 'GLP-1' is the specific active pharmaceutical mechanism of prescription drugs like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro) — these are injectable peptides that directly agonize the glucagon-like peptide-1 receptor. NO oral supplement can produce meaningful GLP-1 receptor agonism at supplement doses — the peptide-mimetic action requires the specific molecular structure of the pharmaceutical drugs. Using 'GLP-1' as a product name implies mechanistic equivalence to Ozempic/Wegovy that isn't supported by any RCT evidence. This category (OTC 'GLP-1 alternatives') is under active FTC scrutiny for deceptive marketing. Whatever herbal/nutrient combination is inside the capsule may have its own modest evidence for glucose/appetite modulation — but the 'GLP-1' branding misrepresents the mechanism. Would move to Standard 55+ with removal of 'GLP-1' framing + honest ingredient-specific positioning.
What are the strongest and weakest aspects of this product?
Strongest: Manufacturing at 55/100 (third-party testing, GMP compliance, and facility audit status) and Safety at 55/100 (adverse-event profile, interaction risk, and dose ceiling). Weakest: Transparency at 40/100 (dose disclosure vs proprietary blends, and honesty of marketing claims) and Evidence at 32/100 (quality of published RCT support for the active ingredients at the label dose). All six dimensions feed the overall Vyvata score; a weakness on any one dimension pulls the overall down proportionally.
Is 21st Century GLP-1 60 Vegetarian Capsules third-party tested?
No third-party certifications (NSF, USP, ConsumerLab, or equivalent) were on record at the time of scoring. This affects the Manufacturing dimension score. The manufacturer may test internally or have obtained certification more recently — check the current product label for the most up-to-date information.
Why was this product auto-rejected?
This product triggered the Vyvata auto-fail rule "unverified_medical_claim", which places it in the Rejected tier regardless of its scores on other dimensions. See the full explanation above and the methodology page for the current list of auto-fail rules.
What would move 21st Century GLP-1 60 Vegetarian Capsules to a higher tier?
Would move to Standard 55+ with removal of 'GLP-1' framing + honest ingredient-specific positioning.
Are there higher-scoring alternatives to 21st Century GLP-1 60 Vegetarian Capsules?
The top-ranked weight management & metabolic health product in the Vyvata catalog is currently Thorne Berberine Dietary Supplement 1000 mg 60 Capsules at 80/100. See the full ranked list of 218 scored products in this subcategory at https://vyvata.com/pages/best-weight-management-and-metabolic-health-supplements-ranked.
What does the Vyvata score mean?
The Vyvata Scoring Framework rates every listed product 0–100 across six dimensions: Evidence, Formulation, Manufacturing, Safety, Transparency, and Sustainability. Tier bands: Elite 85–100 (top-tier evidence + formulation + manufacturing), Verified 70–84 (strong on most dimensions), Standard 50–69 (solid but with weaknesses called out), Rejected 0–49 (specific failures documented). Rejected products remain listed with reasons. Full methodology at https://vyvata.com/pages/methodology.
Where can I read customer reviews for 21st Century GLP-1 60 Vegetarian Capsules?
The Vyvata score measures product integrity against a published rubric, not customer sentiment. For customer reviews and community discussion, search external platforms directly: Amazon (https://www.amazon.com/s?k=21st%20Century%20GLP-1%2060%20Vegetarian%20Capsules),Google(https://www.google.com/search?q=21st%20Century%20GLP-1%2060%20Vegetarian%20Capsules+reviews),Reddit(https://www.reddit.com/search/?q=21st%20Century%20GLP-1%2060%20Vegetarian%20Capsules%20review),andTrustpilot(https://www.trustpilot.com/search?query=21st%20Century%20GLP-1%2060%20Vegetarian%20Capsules).Vyvatadoesnotaggregate,republish,orlicensethosethird-partyreviews.
Customer reviews
Reviews on other platforms
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
All the data we have on this product
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
- VSF score
- 38 / 100
- Tier
- Rejected
- Category
- Supplements
- Subcategory
- weight metabolic health
- Last scored
- Auto-fail rule
unverified_medical_claim- Third-party certifications
- None on record at time of scoring
- Vendor
- Pasteur Pharmacy
- Product type
- Vitamins & Supplements
- Tags
- Pasteur Pharmacy, Shopify Collective
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.
Share
