Optimum Nutrition
THE BIOHACKING STANDARD
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Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
The product title itself is a red flag — 'milk thistle grass' is botanically incorrect (Silybum marianum is not a grass; the active flavonolignan silymarin is concentrated in the seeds, not the leaf or 'grass'). a small third-party seller storefront is a small DTC seller and the naming pattern strongly suggests raw seed or aerial powder rather than a standardized silymarin extract. Combined with dandelion root at unspecified dose in a proprietary blend, this fails on both misleading_naming (mislabeling of botanical part) and sub_therapeutic_dose grounds. Not autofailed for detox marketing, but the botanical inaccuracy plus lack of silymarin standardization keeps this in Rejected tier.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
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Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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