Optimum Nutrition
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Wild Lettuce
Wild Lettuce
No reviews
No reviews
Regular price
$3.80 USD
Regular price
$7.59 USD
Sale price
$3.80 USD
Shipping calculated at checkout.
Quantity
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The full picture
Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
52/100
Rejected
Six-dimension breakdown
Evidence
42
Formulation
55
Manufacturing
58
Safety
52
Transparency
55
Sustainability
50
Why this scored 52/100
Wild lettuce (Lactuca virosa) is a traditional sedative with essentially no modern RCT support. Marketed in some circles as an 'opioid alternative' — the lactucarium sesquiterpene lactones have mild sedative effects at high doses but the psychoactive claims are exaggerated. Weak evidence base overall.
Last scored: Full rubric →
Evidence & sources
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
How to read the Evidence dimension
- 80–100: Multiple double-blind RCTs in indexed journals directly testing this product OR the exact ingredients at the exact dose.
- 60–79: Single double-blind RCT + supporting ingredient literature at the studied dose.
- 40–59: Open-label trials + ingredient literature; no product-specific double-blind evidence.
- 20–39: Ingredient literature only; no product-specific trials or trials in predatory venues.
- 0–19: No credible evidence base or unverifiable claims.
Frequently asked questions
Auto-generated from Vyvata's scoring data for this product. For general questions about the store (shipping, returns, wholesale), see the site FAQ.
What is Wild Lettuce?
Wild Lettuce, categorized under Sleep supplements & nutraceuticals in the Sleep Optimization vertical. It is scored on the Vyvata Scoring Framework — an independent 6-dimension rubric applied uniformly to every product Vyvata lists.
How does Wild Lettuce score on the Vyvata rubric?
52/100 overall — Rejected tier (0–49 band). Per-dimension breakdown: Manufacturing 58, Formulation 55, Transparency 55, Safety 52, Sustainability 50, Evidence 42. Scored as of 2026-08-24.
Why did Wild Lettuce score in the Rejected tier?
Wild lettuce (Lactuca virosa) is a traditional sedative with essentially no modern RCT support. Marketed in some circles as an 'opioid alternative' — the lactucarium sesquiterpene lactones have mild sedative effects at high doses but the psychoactive claims are exaggerated. Weak evidence base overall.
What are the strongest and weakest aspects of this product?
Strongest: Manufacturing at 58/100 (third-party testing, GMP compliance, and facility audit status) and Formulation at 55/100 (dose adequacy, bioavailability form, and ingredient redundancy). Weakest: Sustainability at 50/100 (sourcing practices, packaging, and corporate practice) and Evidence at 42/100 (quality of published RCT support for the active ingredients at the label dose). All six dimensions feed the overall Vyvata score; a weakness on any one dimension pulls the overall down proportionally.
Is Wild Lettuce third-party tested?
No third-party certifications (NSF, USP, ConsumerLab, or equivalent) were on record at the time of scoring. This affects the Manufacturing dimension score. The manufacturer may test internally or have obtained certification more recently — check the current product label for the most up-to-date information.
Are there higher-scoring alternatives to Wild Lettuce?
The top-ranked sleep supplements & nutraceuticals product in the Vyvata catalog is currently Ortho Molecular Products Botanicalm PM 30 Capsules at 73/100. See the full ranked list of 62 scored products in this subcategory at https://vyvata.com/pages/best-sleep-supplements-and-nutraceuticals-ranked.
What does the Vyvata score mean?
The Vyvata Scoring Framework rates every listed product 0–100 across six dimensions: Evidence, Formulation, Manufacturing, Safety, Transparency, and Sustainability. Tier bands: Elite 85–100 (top-tier evidence + formulation + manufacturing), Verified 70–84 (strong on most dimensions), Standard 50–69 (solid but with weaknesses called out), Rejected 0–49 (specific failures documented). Rejected products remain listed with reasons. Full methodology at https://vyvata.com/pages/methodology.
Where can I read customer reviews for Wild Lettuce?
The Vyvata score measures product integrity against a published rubric, not customer sentiment. For customer reviews and community discussion, search external platforms directly: Amazon (https://www.amazon.com/s?k=Wild%20Lettuce),Google(https://www.google.com/search?q=Wild%20Lettuce+reviews),Reddit(https://www.reddit.com/search/?q=Wild%20Lettuce%20review),andTrustpilot(https://www.trustpilot.com/search?query=Wild%20Lettuce).Vyvatadoesnotaggregate,republish,orlicensethosethird-partyreviews.
Customer reviews
Reviews on other platforms
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
All the data we have on this product
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
- VSF score
- 52 / 100
- Tier
- Rejected
- Category
- Supplements
- Subcategory
- sleep supplements nutraceuticals
- Last scored
- Third-party certifications
- None on record at time of scoring
- Vendor
- Swanson Vitamins
- Tags
- Shopify Collective, Swanson Vitamins
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.
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