Optimum Nutrition
THE BIOHACKING STANDARD
Welcome to our store
Couldn't load pickup availability
Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
Generic unit-dose blister-pack vitamin D3 at 400 IU — this is the 1997 IOM Adequate Intake, not a level supported by modern serum 25(OH)D data. Endocrine Society (Holick 2011) and most current supplementation trials use 1000–2000 IU/day minimum for repletion, and the VITAL trial (Manson 2019) used 2000 IU. 400 IU rarely moves serum 25(OH)D meaningfully in deficient adults. Anonymous manufacturer with no brand accountability, no third-party testing, and no cofactors (K2, magnesium). Would move to Standard-Verified at 1000–2000 IU with named manufacturer, USP verification, and K2 MK-7 pairing.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
Auto-generated from Vyvata's scoring data for this product. For general questions about the store (shipping, returns, wholesale), see the site FAQ.
Vitamin D3 10 mcg (400 IU) Tablets, 100 Count, Unit Dose (UD), categorized under Vitamins & foundational micronutrients in the Supplements vertical. It is scored on the Vyvata Scoring Framework — an independent 6-dimension rubric applied uniformly to every product Vyvata lists.
54/100 overall — Rejected tier (0–49 band). Per-dimension breakdown: Evidence 72, Safety 68, Manufacturing 50, Formulation 45, Sustainability 45, Transparency 40. Scored as of 2026-08-24.
Generic unit-dose blister-pack vitamin D3 at 400 IU — this is the 1997 IOM Adequate Intake, not a level supported by modern serum 25(OH)D data. Endocrine Society (Holick 2011) and most current supplementation trials use 1000–2000 IU/day minimum for repletion, and the VITAL trial (Manson 2019) used 2000 IU. 400 IU rarely moves serum 25(OH)D meaningfully in deficient adults. Anonymous manufacturer with no brand accountability, no third-party testing, and no cofactors (K2, magnesium). Would move to Standard-Verified at 1000–2000 IU with named manufacturer, USP verification, and K2 MK-7 pairing.
Strongest: Evidence at 72/100 (quality of published RCT support for the active ingredients at the label dose) and Safety at 68/100 (adverse-event profile, interaction risk, and dose ceiling). Weakest: Sustainability at 45/100 (sourcing practices, packaging, and corporate practice) and Transparency at 40/100 (dose disclosure vs proprietary blends, and honesty of marketing claims). All six dimensions feed the overall Vyvata score; a weakness on any one dimension pulls the overall down proportionally.
No third-party certifications (NSF, USP, ConsumerLab, or equivalent) were on record at the time of scoring. This affects the Manufacturing dimension score. The manufacturer may test internally or have obtained certification more recently — check the current product label for the most up-to-date information.
Would move to Standard-Verified at 1000–2000 IU with named manufacturer, USP verification, and K2 MK-7 pairing.
The top-ranked vitamins & foundational micronutrients product in the Vyvata catalog is currently Thorne Basic Nutrients 2/Day at 89/100. See the full ranked list of 635 scored products in this subcategory at https://vyvata.com/pages/best-vitamins-and-foundational-micronutrients-supplements-ranked.
The Vyvata Scoring Framework rates every listed product 0–100 across six dimensions: Evidence, Formulation, Manufacturing, Safety, Transparency, and Sustainability. Tier bands: Elite 85–100 (top-tier evidence + formulation + manufacturing), Verified 70–84 (strong on most dimensions), Standard 50–69 (solid but with weaknesses called out), Rejected 0–49 (specific failures documented). Rejected products remain listed with reasons. Full methodology at https://vyvata.com/pages/methodology.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. For customer reviews and community discussion, search external platforms directly: Amazon (https://www.amazon.com/s?k=Vitamin%20D3%2010%20mcg%20(400%20IU)%20Tablets%2C%20100%20Count%2C%20Unit%20Dose%20(UD)),Google(https://www.google.com/search?q=Vitamin%20D3%2010%20mcg%20(400%20IU)%20Tablets%2C%20100%20Count%2C%20Unit%20Dose%20(UD)+reviews),Reddit(https://www.reddit.com/search/?q=Vitamin%20D3%2010%20mcg%20(400%20IU)%20Tablets%2C%20100%20Count%2C%20Unit%20Dose%20(UD)%20review),andTrustpilot(https://www.trustpilot.com/search?query=Vitamin%20D3%2010%20mcg%20(400%20IU)%20Tablets%2C%20100%20Count%2C%20Unit%20Dose%20(UD)).Vyvatadoesnotaggregate,republish,orlicensethosethird-partyreviews.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

Optimum Nutrition
Onnit
WOW MD LLC
Prevagen
Find Your Protocol
A few quick questions about your goals and current concerns. We'll build a tailored protocol — a Basics list of essentials plus a comprehensive Biohackers list — across all Vyvata categories.
No signup required · Your protocol is private to you