Optimum Nutrition
THE BIOHACKING STANDARD
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Prem Radiance is a marine collagen + biotin + hyaluronic acid + cordyceps liquid beauty supplement. The formula uses MoriKol® Tripeptide Marine Collagen — a branded ingredient with some published RCT data (Yamashita 2024 and earlier tripeptide fish collagen work by Sugihara 2018 on facial elasticity and hydration at 2-5g/day for 8+ weeks). Marine collagen has moderate evidence at 2.5-10g/day. Biotin at 300-2500mcg has anecdotal skin/hair support but weak RCT evidence outside of overt biotin deficiency. Hyaluronic acid oral (~120mg/day) has some human evidence (Kawada 2014). Cordyceps in a beauty product is unusual — it is more associated with performance and immune positioning. Liquid delivery format has bioavailability arguments and shelf-stability arguments both ways. Held to Standard by (1) proprietary blend risk (dose per ingredient not disclosed at the listing level), (2) 'collagen rebuilding' language that overstates the mechanism (oral collagen breaks into amino acids and short peptides absorbed via intestinal transporters; net skin effect is modest), and (3) cordyceps inclusion without clear beauty-relevant evidence. Standard-tier formulation.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
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Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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