Pharmanex® Nu Biome® Coconut Pineapple Caffeine Free

Six-dimension breakdown

Why this scored 54/100

Nu Biome is Nu Skin's probiotic-prebiotic drink mix, coconut-pineapple caffeine-free variant. Products in this format typically combine one or more probiotic strains (usually Lactobacillus and Bifidobacterium species) with prebiotic fibers (inulin, FOS, resistant starch) and flavoring. The evidence gate for a probiotic product is strain-level specificity — the FDA and every serious systematic review require identification down to the strain (genus + species + strain designation, e.g. Lactobacillus rhamnosus GG or Bifidobacterium lactis BB-12) and per-serving CFU count. Strain evidence is Grade B for specific outcomes (L. rhamnosus GG for pediatric acute diarrhea; B. infantis 35624 for IBS symptoms; VSL#3 for pouchitis). Generic 'probiotic blend' without strain designations has Grade C at best because the outcomes are strain-specific, not species-specific. Whether Nu Biome discloses full strain-level identification and CFU counts is the deciding question. Format as a flavored drink mix is convenient but adds sugar or non-nutritive sweeteners. Standard Nu Skin MLM channel caveats. Sits on Rejected/Standard boundary.

Evidence & sources

The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.

Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.

How to read the Evidence dimension

• 80–100: Multiple double-blind RCTs in indexed journals directly testing this product OR the exact ingredients at the exact dose.
• 60–79: Single double-blind RCT + supporting ingredient literature at the studied dose.
• 40–59: Open-label trials + ingredient literature; no product-specific double-blind evidence.
• 20–39: Ingredient literature only; no product-specific trials or trials in predatory venues.
• 0–19: No credible evidence base or unverifiable claims.

FAQ data has not been generated for this product yet. See the site FAQ for general questions.

Customer reviews

All the data we have on this product

Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.

VSF score

54 / 100

Tier

Rejected

Category

Supplements

Subcategory

gut digestive

Last scored

August 29, 2026

Third-party certifications

None on record at time of scoring

Vendor

Leaders Beauty & Wellness

Tags

Leaders Beauty & Wellness, Shopify Collective

Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.