Optimum Nutrition
THE BIOHACKING STANDARD
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Osha Tincture is single-ingredient liquid tincture Osha (Ligusticum porteri). Osha root is used in Southwestern US and Mexican folk medicine for respiratory complaints. Distinguished from toxic Cicuta (water hemlock) look-alikes only by experienced foragers. No modern RCT evidence. Rests on traditional-use precedent. Contraindicated in pregnancy (uterine stimulant). Sustainability concern — wild-harvested and slow-growing. Traditional use plus documented safety concerns. Garden Organics is a small US-based single-ingredient herbal line; every product is one botanical in capsule or tincture form (no proprietary blends). Third-party COAs, per-lot heavy-metal/microbial data, and specific standardization percentages are not publicly disclosed at the product level, which is a real transparency gap despite the honest single-ingredient formatting.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
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Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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