Optimum Nutrition
THE BIOHACKING STANDARD
Welcome to our store
Couldn't load pickup availability
Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
NusaPure Stinging Nettle uses a 30:1 organic extract at 400 mg per capsule. Stinging nettle (Urtica dioica) has two distinct evidence bases: nettle LEAF for seasonal allergy symptom relief at 300-600 mg standardized freeze-dried extract (Mittman 1990); and nettle ROOT for BPH-associated lower urinary tract symptoms at 300-600 mg standardized methanol extract twice daily (Safarinejad 2005, Ghorbanibirgani 2013). The product does not specify whether it uses leaf or root, does not standardize to a marker compound (scopoletin, sterols for root, or beta-sitosterol), and the 30:1 extraction ratio (implying 12 g raw equivalent per 400 mg dose) is not the same as the freeze-dried or methanol-standardized extracts used in trials. Without part-of-plant disclosure and marker standardization, class-level evidence does not attach. Rejected under sub_therapeutic_dose due to non-standardized preparation.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
FAQ data has not been generated for this product yet. See the site FAQ for general questions.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

Optimum Nutrition
Onnit
WOW MD LLC
Prevagen
Find Your Protocol
A few quick questions about your goals and current concerns. We'll build a tailored protocol — a Basics list of essentials plus a comprehensive Biohackers list — across all Vyvata categories.
No signup required · Your protocol is private to you