NusaPure Pregnenolone (Micronized) 100 mg Per Serving 200 Veg Caps Dietary Supplement Vegan, Non-GMO

NusaPure Pregnenolone (Micronized) 100 mg Per Serving 200 Veg Caps Dietary Supplement Vegan, Non-GMO is a product from NusaPure, categorized under Hormonal health & endocrine support in the Supplements vertical. It is scored on the Vyvata Scoring Framework — an independent 6-dimension rubric applied uniformly to every product Vyvata lists.

58/100 overall — Standard tier (50–69 band). Per-dimension breakdown: Formulation 65, Transparency 65, Evidence 55, Manufacturing 55, Sustainability 50, Safety 48. Scored as of 2026-08-24.

Pregnenolone is an endogenous prohormone (precursor to DHEA, cortisol, and sex steroids) with limited controlled human trials in supplement form. Micronization is a genuine formulation upgrade for oral bioavailability. Real safety concerns: unpredictable downstream conversion to androgens/estrogens, potential hormone-sensitive cancer contraindication, and drug interactions — none flagged on title. 100mg is a high dose; TrueMedX and Life Extension typically dose 25-50mg with practitioner guidance. Would move to Standard 65+ with lower default dose, practitioner-guidance language, and safety warnings for hormone-sensitive conditions.

Strongest: Formulation at 65/100 (dose adequacy, bioavailability form, and ingredient redundancy) and Transparency at 65/100 (dose disclosure vs proprietary blends, and honesty of marketing claims). Weakest: Sustainability at 50/100 (sourcing practices, packaging, and corporate practice) and Safety at 48/100 (adverse-event profile, interaction risk, and dose ceiling). All six dimensions feed the overall Vyvata score; a weakness on any one dimension pulls the overall down proportionally.

No third-party certifications (NSF, USP, ConsumerLab, or equivalent) were on record at the time of scoring. This affects the Manufacturing dimension score. The manufacturer may test internally or have obtained certification more recently — check the current product label for the most up-to-date information.

Would move to Standard 65+ with lower default dose, practitioner-guidance language, and safety warnings for hormone-sensitive conditions.

The top-ranked hormonal health & endocrine support product in the Vyvata catalog is currently Testolite® Corti-Guard at 67/100. See the full ranked list of 87 scored products in this subcategory at https://vyvata.com/pages/best-hormonal-health-and-endocrine-support-supplements-ranked.

The Vyvata Scoring Framework rates every listed product 0–100 across six dimensions: Evidence, Formulation, Manufacturing, Safety, Transparency, and Sustainability. Tier bands: Elite 85–100 (top-tier evidence + formulation + manufacturing), Verified 70–84 (strong on most dimensions), Standard 50–69 (solid but with weaknesses called out), Rejected 0–49 (specific failures documented). Rejected products remain listed with reasons. Full methodology at https://vyvata.com/pages/methodology.

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