Optimum Nutrition
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Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
American skullcap (Scutellaria lateriflora) has one small RCT showing acute anxiolytic effect (Wolfson & Hoffmann 2003) but limited replication. This 66.66mg of a 30:1 extract equates to roughly 2g raw-herb equivalent — modest but on the low end of traditional dosing (350mg-2g). Species is not clearly labeled (S. lateriflora vs S. baicalensis have different actives and hepatotoxicity signals). USDA Organic is a plus for sustainability. Would move to Verified 70+ with species disclosure, flavonoid standardization (baicalin or scutellarin), and identity testing.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
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NusaPure Organic Skullcap Root 30:1 Extract, 66.66 mg Per Veggie Caps 120 Count (Non-GMO, Vegan) is a product from NusaPure, categorized under Stress, mood & mental wellness in the Supplements vertical. It is scored on the Vyvata Scoring Framework — an independent 6-dimension rubric applied uniformly to every product Vyvata lists.
57/100 overall — Standard tier (50–69 band). Per-dimension breakdown: Transparency 68, Safety 60, Evidence 55, Formulation 55, Manufacturing 55, Sustainability 55. Scored as of 2026-08-24.
American skullcap (Scutellaria lateriflora) has one small RCT showing acute anxiolytic effect (Wolfson & Hoffmann 2003) but limited replication. This 66.66mg of a 30:1 extract equates to roughly 2g raw-herb equivalent — modest but on the low end of traditional dosing (350mg-2g). Species is not clearly labeled (S. lateriflora vs S. baicalensis have different actives and hepatotoxicity signals). USDA Organic is a plus for sustainability. Would move to Verified 70+ with species disclosure, flavonoid standardization (baicalin or scutellarin), and identity testing.
Strongest: Transparency at 68/100 (dose disclosure vs proprietary blends, and honesty of marketing claims) and Safety at 60/100 (adverse-event profile, interaction risk, and dose ceiling). Weakest: Manufacturing at 55/100 (third-party testing, GMP compliance, and facility audit status) and Sustainability at 55/100 (sourcing practices, packaging, and corporate practice). All six dimensions feed the overall Vyvata score; a weakness on any one dimension pulls the overall down proportionally.
No third-party certifications (NSF, USP, ConsumerLab, or equivalent) were on record at the time of scoring. This affects the Manufacturing dimension score. The manufacturer may test internally or have obtained certification more recently — check the current product label for the most up-to-date information.
Would move to Verified 70+ with species disclosure, flavonoid standardization (baicalin or scutellarin), and identity testing.
The top-ranked stress, mood & mental wellness product in the Vyvata catalog is currently Momentous Sleep at 77/100. See the full ranked list of 247 scored products in this subcategory at https://vyvata.com/pages/best-stress-mood-and-mental-wellness-supplements-ranked.
The Vyvata Scoring Framework rates every listed product 0–100 across six dimensions: Evidence, Formulation, Manufacturing, Safety, Transparency, and Sustainability. Tier bands: Elite 85–100 (top-tier evidence + formulation + manufacturing), Verified 70–84 (strong on most dimensions), Standard 50–69 (solid but with weaknesses called out), Rejected 0–49 (specific failures documented). Rejected products remain listed with reasons. Full methodology at https://vyvata.com/pages/methodology.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. For customer reviews and community discussion, search external platforms directly: Amazon (https://www.amazon.com/s?k=NusaPure%20NusaPure%20Organic%20Skullcap%20Root%2030%3A1%20Extract%2C%2066.66%20mg%20Per%20Veggie%20Caps%20120%20Count%20(Non-GMO%2C%20Vegan)),Google(https://www.google.com/search?q=NusaPure%20NusaPure%20Organic%20Skullcap%20Root%2030%3A1%20Extract%2C%2066.66%20mg%20Per%20Veggie%20Caps%20120%20Count%20(Non-GMO%2C%20Vegan)+reviews),Reddit(https://www.reddit.com/search/?q=NusaPure%20NusaPure%20Organic%20Skullcap%20Root%2030%3A1%20Extract%2C%2066.66%20mg%20Per%20Veggie%20Caps%20120%20Count%20(Non-GMO%2C%20Vegan)%20review),andTrustpilot(https://www.trustpilot.com/search?query=NusaPure%20NusaPure%20Organic%20Skullcap%20Root%2030%3A1%20Extract%2C%2066.66%20mg%20Per%20Veggie%20Caps%20120%20Count%20(Non-GMO%2C%20Vegan)).Vyvatadoesnotaggregate,republish,orlicensethosethird-partyreviews.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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