Optimum Nutrition
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Luteolin and rutin are flavonoids with preclinical anti-inflammatory and mast-cell-stabilizing activity (Theoharides 2015 luteolin), and rutin has vein-tonic evidence. The 200 mg total for a 'complex' means the individual mg of luteolin vs rutin is not disclosed on the title, a transparency gap. Human RCTs at this dose are limited. Vegan/Non-GMO framing is honest. Would move to Standard 62+ with per-actives disclosure and 65+ with human clinical support at the label dose.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
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NusaPure Luteolin Complex with Rutin 200 mg | 100 Capsules | Vegetarian, Non-GMO & Vegan Flavonoid Formula is a product from NusaPure, categorized under Immune health & antioxidants in the Supplements vertical. It is scored on the Vyvata Scoring Framework — an independent 6-dimension rubric applied uniformly to every product Vyvata lists.
57/100 overall — Standard tier (50–69 band). Per-dimension breakdown: Safety 62, Evidence 58, Formulation 55, Manufacturing 55, Transparency 55, Sustainability 55. Scored as of 2026-08-24.
Luteolin and rutin are flavonoids with preclinical anti-inflammatory and mast-cell-stabilizing activity (Theoharides 2015 luteolin), and rutin has vein-tonic evidence. The 200 mg total for a 'complex' means the individual mg of luteolin vs rutin is not disclosed on the title, a transparency gap. Human RCTs at this dose are limited. Vegan/Non-GMO framing is honest. Would move to Standard 62+ with per-actives disclosure and 65+ with human clinical support at the label dose.
Strongest: Safety at 62/100 (adverse-event profile, interaction risk, and dose ceiling) and Evidence at 58/100 (quality of published RCT support for the active ingredients at the label dose). Weakest: Transparency at 55/100 (dose disclosure vs proprietary blends, and honesty of marketing claims) and Sustainability at 55/100 (sourcing practices, packaging, and corporate practice). All six dimensions feed the overall Vyvata score; a weakness on any one dimension pulls the overall down proportionally.
No third-party certifications (NSF, USP, ConsumerLab, or equivalent) were on record at the time of scoring. This affects the Manufacturing dimension score. The manufacturer may test internally or have obtained certification more recently — check the current product label for the most up-to-date information.
Would move to Standard 62+ with per-actives disclosure and 65+ with human clinical support at the label dose.
The top-ranked immune health & antioxidants product in the Vyvata catalog is currently PreserVision AREDS 2 Eye Vitamins, 210 Soft gels at 77/100. See the full ranked list of 590 scored products in this subcategory at https://vyvata.com/pages/best-immune-health-and-antioxidants-supplements-ranked.
The Vyvata Scoring Framework rates every listed product 0–100 across six dimensions: Evidence, Formulation, Manufacturing, Safety, Transparency, and Sustainability. Tier bands: Elite 85–100 (top-tier evidence + formulation + manufacturing), Verified 70–84 (strong on most dimensions), Standard 50–69 (solid but with weaknesses called out), Rejected 0–49 (specific failures documented). Rejected products remain listed with reasons. Full methodology at https://vyvata.com/pages/methodology.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. For customer reviews and community discussion, search external platforms directly: Amazon (https://www.amazon.com/s?k=NusaPure%20NusaPure%20Luteolin%20Complex%20with%20Rutin%20200%20mg%20%7C%20100%20Capsules%20%7C%20Vegetarian%2C%20Non-GMO%20%26%20Vegan%20Flavonoid%20Formula),Google(https://www.google.com/search?q=NusaPure%20NusaPure%20Luteolin%20Complex%20with%20Rutin%20200%20mg%20%7C%20100%20Capsules%20%7C%20Vegetarian%2C%20Non-GMO%20%26%20Vegan%20Flavonoid%20Formula+reviews),Reddit(https://www.reddit.com/search/?q=NusaPure%20NusaPure%20Luteolin%20Complex%20with%20Rutin%20200%20mg%20%7C%20100%20Capsules%20%7C%20Vegetarian%2C%20Non-GMO%20%26%20Vegan%20Flavonoid%20Formula%20review),andTrustpilot(https://www.trustpilot.com/search?query=NusaPure%20NusaPure%20Luteolin%20Complex%20with%20Rutin%20200%20mg%20%7C%20100%20Capsules%20%7C%20Vegetarian%2C%20Non-GMO%20%26%20Vegan%20Flavonoid%20Formula).Vyvatadoesnotaggregate,republish,orlicensethosethird-partyreviews.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
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Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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