Optimum Nutrition
THE BIOHACKING STANDARD
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Everything Vyvata knows about this product — the score, the evidence, the FAQ, and where else to find shopper reviews. No hidden data. Every vendor is scored on the same published rubric — no brand can pay for placement. Read the rubric →
Fo-Ti (Polygonum multiflorum / He Shou Wu) has significant hepatotoxicity signals in case reports and pharmacovigilance data (Lin 2015 review of case series). Raw and processed forms have different toxicity profiles. Marketing for hair-graying reversal isn't RCT-supported. Safety concerns drive the low score. Would need Fo-Ti removed from OTC channels; not appropriate to score higher regardless of dose.
The Vyvata score's Evidence dimension measures the quality of published RCT support for a product's active ingredients at the label dose. Our source hierarchy: double-blind RCTs in MEDLINE-indexed journals > single-blind RCTs > open-label trials > observational studies > mechanism papers > N=1 case studies (anecdotes). Predatory journals and manufacturer-authored studies without independent replication are weighted down.
Product-specific evidence citations for this item are embedded in the analysis text on the "Analysis" tab. For the full framework and evidence hierarchy, see the methodology page.
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NusaPure Fo-Ti 30:1 Extract, 167 mg per Veg Caps, 200 Count, Non-GMO, Vegan, Bioperine is a product from NusaPure, categorized under Skin, hair & beauty supplements in the Supplements vertical. It is scored on the Vyvata Scoring Framework — an independent 6-dimension rubric applied uniformly to every product Vyvata lists.
50/100 overall — Rejected tier (0–49 band). Per-dimension breakdown: Formulation 55, Manufacturing 55, Transparency 55, Sustainability 55, Evidence 40, Safety 40. Scored as of 2026-08-24.
Fo-Ti (Polygonum multiflorum / He Shou Wu) has significant hepatotoxicity signals in case reports and pharmacovigilance data (Lin 2015 review of case series). Raw and processed forms have different toxicity profiles. Marketing for hair-graying reversal isn't RCT-supported. Safety concerns drive the low score. Would need Fo-Ti removed from OTC channels; not appropriate to score higher regardless of dose.
Strongest: Formulation at 55/100 (dose adequacy, bioavailability form, and ingredient redundancy) and Manufacturing at 55/100 (third-party testing, GMP compliance, and facility audit status). Weakest: Evidence at 40/100 (quality of published RCT support for the active ingredients at the label dose) and Safety at 40/100 (adverse-event profile, interaction risk, and dose ceiling). All six dimensions feed the overall Vyvata score; a weakness on any one dimension pulls the overall down proportionally.
No third-party certifications (NSF, USP, ConsumerLab, or equivalent) were on record at the time of scoring. This affects the Manufacturing dimension score. The manufacturer may test internally or have obtained certification more recently — check the current product label for the most up-to-date information.
The top-ranked skin, hair & beauty supplements product in the Vyvata catalog is currently Pure Encapsulations Hair/Skin/Nails Ultra – Advanced Beauty Supplement with Biotin & Collagen - 60 Capsules at 78/100. See the full ranked list of 264 scored products in this subcategory at https://vyvata.com/pages/best-skin-hair-and-beauty-supplements-ranked.
The Vyvata Scoring Framework rates every listed product 0–100 across six dimensions: Evidence, Formulation, Manufacturing, Safety, Transparency, and Sustainability. Tier bands: Elite 85–100 (top-tier evidence + formulation + manufacturing), Verified 70–84 (strong on most dimensions), Standard 50–69 (solid but with weaknesses called out), Rejected 0–49 (specific failures documented). Rejected products remain listed with reasons. Full methodology at https://vyvata.com/pages/methodology.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. For customer reviews and community discussion, search external platforms directly: Amazon (https://www.amazon.com/s?k=NusaPure%20NusaPure%20Fo-Ti%2030%3A1%20Extract%2C%20167%20mg%20per%20Veg%20Caps%2C%20200%20Count%2C%20Non-GMO%2C%20Vegan%2C%20Bioperine),Google(https://www.google.com/search?q=NusaPure%20NusaPure%20Fo-Ti%2030%3A1%20Extract%2C%20167%20mg%20per%20Veg%20Caps%2C%20200%20Count%2C%20Non-GMO%2C%20Vegan%2C%20Bioperine+reviews),Reddit(https://www.reddit.com/search/?q=NusaPure%20NusaPure%20Fo-Ti%2030%3A1%20Extract%2C%20167%20mg%20per%20Veg%20Caps%2C%20200%20Count%2C%20Non-GMO%2C%20Vegan%2C%20Bioperine%20review),andTrustpilot(https://www.trustpilot.com/search?query=NusaPure%20NusaPure%20Fo-Ti%2030%3A1%20Extract%2C%20167%20mg%20per%20Veg%20Caps%2C%20200%20Count%2C%20Non-GMO%2C%20Vegan%2C%20Bioperine).Vyvatadoesnotaggregate,republish,orlicensethosethird-partyreviews.
The Vyvata score measures product integrity against a published rubric, not customer sentiment. Vyvata does not aggregate, republish, or license third-party reviews — the links below open search pages on their respective platforms.
Every VSF-related metafield surfaced verbatim. Nothing hidden. If you spot data that looks wrong, let us know.
Every score is set from the published rubric, audit-logged, and rescored whenever new evidence emerges (published trials, updated labels, third-party testing releases). Every vendor is scored on the same criteria — no pay-to-play. See our editorial-independence disclosure for the full policy, including brands with an editorial relationship to this site.

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